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September 2009 Issue        
In This Issue
The People Behind CWW: Dr. Jeremiahs Twa-Twa of Uganda
CWW Success Story: Lao PDR
Highlighting Program Effectiveness with Treatment Coverage Metrics
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Greetings!
Kim Koporc CCW Acting DirectorOne of the biggest challenges our program, and other programs like Children Without Worms (CWW) face, is evaluating program effectiveness. Key to this evaluation is monitoring drug coverage--the percent of people in a targeted population who ingested the drug or drug combinations. In this issue, we describe CWW's approach to monitoring drug coverage, highlighting the new World Health Organization (WHO) guide to monitoring drug coverage upon which we based much of our approach.

In this issue, we also describe the work of Dr. Jeremiahs Twa-Twa of Uganda's Ministry of Health. Dr. Twa-Twa manages his country's Child Health Days Plus program, which delivers critical child health interventions, including bi-annual deworming. We next place the spotlight on the program in Lao PDR, where a tight collaboration between the Ministry of Health and the Ministry of Education has resulted in a highly effective school-based deworming program.

I hope you are as energized as I am by the successes of our program. I feel so fortunate to work with such dedicated people in a program that helps so many children lead healthier, worm-free lives.

Thank you for taking the time to learn more about Children Without Worms.

Sincerely,

Kim Koporc
Acting Director
Children Without Worms

 The People Behind CWW: Dr. Jeremiahs Twa-Twa of Uganda
Jeremiahs Twa-TwaAs the Assistant Commissioner of Health Services in the Child Health Division of Uganda's Ministry of Health (MoH), Dr. Jeremiahs Twa-Twa is responsible for managing the activities of the Child Health Days Plus program. This program combines numerous health interventions for Uganda's 14 million preschool and school age children, and for women of childbearing age. Interventions include administering immunizations, providing vitamin A supplements, deworming children, promoting breastfeeding up to 6 months, improving sanitation and hygiene, and providing insecticide treated bed nets. The "Plus" component addresses Neglected Tropical Diseases (NTDs), vision screening, and early infant diagnosis of HIV/AIDS to administer early antiretroviral therapy. By combining resources targeted toward preschool and school age children, Uganda provides cost-effective health interventions to both age groups in a single program.

The MoH selected Dr. Twa-Twa to run the Child Health Days program because of his vast experience working in public health in a career that spans 30 years. Early on, he worked as a general doctor in local communities, and later, as a Director of District Health Services. In these positions, he became familiar with the common health issues like malaria, worms, and other NTDs that people, especially the poor, experience. Dr. Twa-Twa then moved to the MoH headquarters, where he played a critical role in collecting the surveillance data used to demonstrate the emerging issue of HIV/AIDS in Uganda. He was then promoted to Registrar of the Uganda Medical and Dental Practitioners Council, a position he held for close to five years before accepting his current position in 2004.

For Dr. Twa-Twa, job satisfaction comes from identifying what public health work needs to be done, developing a plan, and seeing the benefits that occur from implementing the plan. He is particularly proud of the Child Health Days Plus bi-annual deworming efforts and its continued progress. He sees the mebendazole donations from Johnson & Johnson through Children Without Worms (CWW) as key to this progress. He states that, "The de-worming coverage has progressively improved from 40 percent when the program started in 2004, to 70 percent in 2008.

Dr. Twa-Twa believes the program succeeds because of the tremendous support from top MoH leadership. He says, "The Director General of Health services of the Ministry of Health Dr. Sam Zaramba is very keen about the deworming and neglected tropical diseases program and about having the program's activities implemented." He also attributes program success to the commitment by and effective collaboration with numerous partners, including CWW, the United Nations World Food Program, UNICEF, the World Health Organization (WHO), and USAID's A2Z micronutrient program. But the understated Dr. Twa-Twa is always at work on behalf of the program. Any given day might find him in meetings with program stakeholders or others in the health sector, on field visits to distribution sites, and writing reports and correspondence.

Dr. Twa-Twa notes the challenge of getting the donated mebendazole into Uganda and out to the point-of-use on time to take full advantage of the bi-annual mobilization efforts. He also says that collecting data from the deworming sites is difficult, so assessing and reporting program progress to the MoH, CWW and other stakeholders is often delayed. Fortunately, a planned MoH partnership with the School of Public Health and other training institutions will address this second challenge. The schools will assign students to districts for 2 to 3 months a year as part of the training program, providing the much-needed program support at the district level for planning, implementation, data retrieval, and timely report submission. This arrangement will also prepare individuals to serve as district health workers in the future.

Although Dr. Twa-Twa says that the ultimate goal of the deworming efforts is to reach 100 percent of the 14 million children in Uganda, he notes that "Public health programs take time, and you have to keep them going." He says, "However, we are moving forward." And with a 30 percent increase in de-worming coverage, Uganda is clearly poised to reach that ultimate goal in the near future. Dr. Twa-Twa thanks CWW for joining hands with other development partners and the Ugandan government to improve the quality of life for Uganda's children.

 Leveraging Partner and Stakeholder Support for Success
Lao PDR Meeting Lao People's Democratic Republic (PDR), is a landlocked country bordered by Vietnam to the east and Thailand to the west. According to Dr. Chitsavang Chanthavisouk, Lao PDR Coordinator for the School Health Program, a 2002 parasitological survey revealed that over 90 percent of school age children in Laos were infected with soil-transmitted helminthes (STH). The survey results, coupled with encouragement from the World Health Organization (WHO), persuaded the Laotian government to establish a deworming program in 2005.

Since the deworming program started, the 2006 survey showed a reduction in STH infection prevalence from 90 percent in 2002 to 64 percent. A 2008 survey indicated a further reduction to 56 percent.

While the reduced infection rates indicate program success, there's a second success story--one that revolves around achieving buy-in from and participation by multiple groups, including the Lao PDR Ministries of Health and Education (MoH and MoE), community leaders, parents, and teachers. In particular, the School Health Task Force (SHTF), a collaboration of the MoH with the MoE, establishes an approach worth replicating elsewhere. In this collaboration, the MoE coordinates among the educational administrators to implement the program, and the MoH provides technical backup, coordinates funding and drug donations, and stores and transports the drugs.

Dr. Padmasiri Aratchige, Inter-country Program Officer for Parasitic Diseases Control explained how these parties joined forces. First, WHO recognized the critical need for deworming in Lao PDR, providing health experts like Dr. Aratchige and Dr. Chanthavisouk and identifying ways for the Lao PDR MoH and the MoE to collaborate. With the backing and official recognition of the Laotian government, the two Ministries signed a memorandum of understanding to create the SHTF, the document that defined how the ministries would coordinate the national and province/district deworming efforts.

Dr. Aratchige notes that a spirit of volunteerism, part of the Laotian and Buddhist culture, also contributes to the program's success. The approximately 20 national and 10 province/district members of the SHTF meet regularly, receiving no additional payment for holding and attending these meetings. The teachers implementing the program also put in unpaid time to distribute the deworming medication, attend trainings and educate the students about the infection cycle and using proper hygiene. For these teachers, Dr. Aratchige says, the reward is observing "the children, after the worms are removed, increasing [school] attendance and improving memory and learning."

Fortunately, deworming also gained community support. Dr. Aratchige states that the side effects of the drugs are, "almost nil, so their [the communities'] experience taking these drugs has been positive, making it far easier to promote the program." Dr. Aratchige further notes, "The parents [of the school children] are very happy and come to the school and ask for deworming for the children."

Dr. Aratchige states that early on the program was challenged by the short-term commitment of drug donors and the less predictable quality of the drugs. In 2008, Children Without Worms (CWW) began supporting the Lao PDR deworming program by giving a long-term commitment to donating its high-quality mebendazole. According to Dr. Aratchige, because of this commitment from CWW, the program can now devote energy to developing a long-term, self-sustaining strategy for deworming.

Dr. Aratchige says that the program faces additional challenges, including a lack of financial and human resources to set up the drug distribution infrastructure, monitor the program effectiveness, and break the infection cycle with improved sanitation. In spite of these challenges, he sees the program as highly successful and notes the importance of continuing to work toward its sustainability.

 Highlighting Program Effectiveness With Treatment Coverage Metrics
Ugandan NurseTreatment coverage, the percentage of individuals in a defined population that ingested a specific administered drug or drug combination, is a critical measurement that disease control programs like Children Without Worms (CWW) can make to demonstrate program effectiveness. As a program with numerous stakeholders, including program sponsors, country governments, partners and volunteers, as well as the people in its target communities, CWW understands the importance of capturing and reporting this metric.


The Importance of Monitoring Treatment Coverage

Monitoring drug treatment coverage provides numerous benefits to a disease control or Preventive Chemotherapy (PCT) program, providing information that:
  • Enables informed decision- and policy-making.
  • Reveals problems, like drug distribution issues, so that corrective action can be taken
  • Provides evidence to program funders, drug donors, and country governments to justify maintaining the program.
  • Increases program compliance by target communities when community members know that many people are being treated.
  • Improves morale of program partners and volunteers when they see the positive impact of their efforts.
  • Strengthens advocacy for the program because stakeholders know that in-need populations are getting treated.
  • Assists in forecasting future drug supply needs.
The CWW Approach to Monitoring Treatment Coverage
CWW tapped into the expertise of the neglected tropical disease (NTD) groups at both RTI and the World health Organization (WHO) to develop a well-constructed approach to and guidelines for monitoring treatment coverage. In this approach, CWW defines treatment coverage as:

                  PCT Equation

Establishing a clear denominator in the equation--all school-age children (5 to 14 years old) living in a targeted district--was critical, as this can be easily taken from national census data and is clearly understood by all program stakeholders. And because CWW defines the implementation unit as a district, coverage rates can be easily compared across districts. Also, if a national deworming campaign uses more than one type of benzimidazole or different sources of the same type of benzimidazole, CWW requests programs use only mebendazole donated by Johnson & Johnson to treat school age children in targeted districts. This approach ensures that only those who have ingested mebendazole from Johnson & Johnson are included in the tally for the numerator and the program can more accurately monitor for adverse effects and drug efficacy because the drug quality is consistent in a defined area.

To verify the accuracy of collected data, CWW is field-testing a survey protocol in Cambodia and Cameroon. The survey, developed with assistance from the Centers for Disease Control and Prevention (CDC), verifies the reported coverage rate and also helps determine how accessible mebendazole is to school-age children not enrolled in school in areas where school attendance is low. The survey tool additionally assesses knowledge, attitudes, and practices around STH infection and helps determine the prevalence, accessibility and use of sanitary latrines and potable water at schools.

Further Guidance on Monitoring Treatment Coverage
CWW's approach and guidelines for monitoring treatment coverage are complementary to those published in Monitoring Drug Coverage for Preventive Chemotherapy, a guide developed by the WHO's Department of NTDs that was released in July of this year. The guide provides best practices and information around monitoring treatment coverage for PCT programs to control NTDs and is a recommended source other PCT programs can turn to when they need to monitor treatment coverage.

If you are interested in learning more, please visit the Children Without Worms web site or fill out the contact form on our site.
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