As reflexology and other CAM practices go mainstream, existing hospital programs provide examples of how the practices are integrated into traditional medicine. The CAM practices are judged on how they meet established criteria for medical practices: safety, efficacy, mechanism of action and cost effectiveness. A study at one Minneapolis hospital is an example of how traditional medicine is working to ascertain if CAM practices meet these criteria and how they can be integrated into hospital use. Paired with philanthropic funding, the hospital research explored how CAM practices can help relieve pain, a concern of the hospital staff and patients. In this study, the mechanism of action of all CAM practices provided is a given: eliciting the relaxation response. In addition, we present an article that notes the various ways hospitals across the country are implementing integrative medicine (IM) programs that include reflexology.