Recently the National Institute of Mental Health reported on “the first long-term, large-scale study designed to determine the safety and effectiveness of treating preschoolers who have attention deficit/hyperactivity disorder (ADHD) with methylphenidate (Ritalin).” The study was published in the Journal of the American Academy of Child and Adolescent Psychiatry.

The study looked at 300 preschoolers, ages 3-5. The children had been diagnosed with ADHD and their families had all been in a 10-week behavior modification program first.

"The Preschool ADHD Treatment Study, or PATS, provides us with the best information to date about treating very young children diagnosed with ADHD," said NIMH Director Thomas R. Insel, MD. "The results show that preschoolers may benefit from low doses of medication when it is closely monitored, but the positive effects are less evident and side-effects are somewhat greater than previous reports in older children."

There are three key points to Dr. Insel’s quote:

1. Preschoolers may benefit -- from low doses -- if closely monitored;
2. But there are not a lot of positive benefits, and
3. The side-effects are worse then in older children

Why does it seem like so many kids today are being labeled ADHD or hyperactive? While my friends tell me that ADHD is a conspiracy by the drug companies to sell more drugs, others tell me that ADHD is just a label given to kids that are “brats.” Is this so? What's the real information on ADHD?

Well, the truth is that Attention Deficit Hyperactivity affects between five to ten percent (5% - 10%) of all children in the United States, and three to six percent (3% - 6%) of adults. About 35% of all children referred to mental health clinics are referred for Attention Deficit Hyperactivity Disorder, making it one of the most prevalent of all childhood psychiatric disorders.

The 5% number is a solid, conservative number supported by a lot of research. Even at 5% each classroom in America will have one or two (2) ADHD kids in the class. So it is a very significant problem across America.

When only Parent Rating Scales are used in a research project, the numbers will range from a low of seven percent (7%) of school-aged children to a high of twenty-three percent (23%) of children.

From the National Institute of Mental Health.

The severity of attention deficit hyperactivity disorder (ADHD) symptoms in youth appears to be reflected in their brain structure, recent NIMH-supported brain imaging studies are finding. In one study, researchers found that the front part of the brain's memory hub, the hippocampus, tended to be enlarged in ADHD, particularly in children with fewer symptoms. They suggest that such changes might develop as a compensatory response that helps the child cope with the impatience and stimulus-seeking problems of the disorder.

The researchers also found that parts of an emotion-processing hub, the amygdala, were smaller in children with the disorder. The diminished size had a significant and positive correlation with severity of ADHD symptoms. In those with the disorder, researchers also observed poor connections between the amygdala and the pre-frontal cortex, which could contribute to problems with impulse control and goal-directed behaviors.

Drs. Kerstin Plessen and Bradley Peterson (Columbia University; New York State Psychiatric Institute; University of Bergen, Norway; and Pennsylvania State University) and colleagues used magnetic resonance imaging (MRI) to scan 51 children and adolescents with ADHD and 63 healthy peers in the study, reported in the July 3, 2006, issue of the Archives of General Psychiatry.