From the Co-Chairs...
We are excited to be producing the first ECOG-ACRIN newsletter, the latest in a series of developments in our new organization. Over the past few months, we have adopted a constitution, opened our first joint trial, launched a website, received our first joint grant award, and solidified committee leaderships. Operational working groups are making progress in organizing our information technology platform and associated informatics capabilities, and the Biomarker Sciences research area leaders are integrating our developmental therapeutics, pathology and lab sciences, and experimental imaging committees. Thoughtful new scientific concepts with integrated therapeutic and diagnostic imaging components are now bubbling up through the various committees to the Executive Review Committee, which is meeting monthly to review these ideas.


The purpose of this newsletter is to keep members and constituents apprised of the latest news from our researchers, highlight recent accomplishments, and provide information on the organization. Certainly, the Group is experiencing a tremendous level of activity right now-and will for several months to come-as it prepares applications for Federal funding in response to the various funding opportunity announcements issued recently by the National Cancer Institute, which are due January 15, 2013; hosts a workshop for imaging researchers and technologists in October; and plans the agenda for the November semi-annual Group meeting. We look forward to sharing information and perspectives about these and other activities via this periodic newsletter.


Robert L. Comis, MD             Mitchell D. Schnall, MD, PhD
Co-Chair                               Co-Chair
2012 ASCO Humanitarian Award
Edith Peterson Mitchell, MD, FACP, a long-time member of ECOG and Co-Chair of the ECOG-ACRIN Cancer Research Group Underserved Populations Subcommittee, has received the American Society of Clinical Oncology (ASCO) 2012 Humanitarian Award, an honor bestowed for her continued dedication to the advancement of ASCO's mission and values and for her exemplary delivery of patient care. Dr. Mitchell accepted the award during the opening session of the ASCO annual meeting in Chicago in June.


Open Letter to Community-based Members  

As the ECOG-ACRIN leadership develop plans for carrying out their scientific program, they are eager to learn more about imaging research interests at community-based sites.

In an open letter, Mitchell D. Schnall, MD, PhD and Group Co-Chair, discusses new outreach efforts to promote imaging research at the community level. He acknowledges that although many ECOG sites have some experience with imaging studies, obtaining the imaging qualifications needed to participate in imaging research could be a challenge for sites new to the process. Dr. Schnall asks that all incoming community-based members affiliated with ECOG introduce imaging colleagues (radiologists, nuclear medicine physicians, and physicists) within their respective institutions and/or networks to ECOG-ACRIN and the many exciting research opportunities available through the organization.

Read more...  


Site Activations for E2410 Gaining Momentum

ECOG-ACRIN is making strides in the activation of E2410, a phase 2 study of response-adapted chemotherapy based on positron emission tomography (PET) in patients with unfavorable stage I/II Hodgkin's lymphoma.

At present, two sites-the Stanford Cancer Center (Stanford, CA) and the McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center (Reading, PA)-have met all requirements and are recruiting patients. About 25 other locations are in advanced stages of completing imaging prequalifications and obtaining institutional review board approvals. The goal is to recruit 200 patients to this study.


Publication News

In this section, we report on original articles authored by members of the ECOG-ACRIN Cancer Research Group and published in the medical journals:

Results of AML Mutational Analysis Published in the
New England Journal of Medicine.
Role of Obesity in HR+ Breast Cancer Studied

Benefit of Supplemental Mammography Reported
First SOAPP manuscript published.

September 2012
In This Issue
ASCO Honors Dr. Mitchell
E2410 Gains Momentum
Publication News
Network News Covers Study
New Forum for Imagers
Upcoming Meetings

Imaging Researchers'  Workshop - by invitation, October 4, 2012, Arlington, VA

ECOG-ACRIN Semi-annual Group Meeting - November 9-11, 2012, Hollywood, FL

Obesity Study Receives Network News Coverage

On August 27, 2012, both the CBS Evening News with Scott Pelley and the NBC Nightly News with Brian Williams carried stories on the results of the ECOG-led analysis entitled "Obesity at diagnosis is associated with inferior outcomes in hormone receptor-positive operable breast cancer," which was published online the same day in CANCER, a journal of the American Cancer Society.     

ECOG-ACRIN Presentations at ASCO 2012

The ECOG-ACRIN Cancer Research Group was well represented at the 48th annual American Society of Clinical Oncology meeting held in Chicago, June 1-5, 2012. We presented at 26 sessions, with topics spanning our research agenda and committees.



ECOG-ACRIN Hosts New Forum for Imagers

The ECOG-ACRIN Cancer Research Group has invited community-based imagers from a variety of clinical settings and areas of expertise to participate in a day-long workshop to discuss the current state of oncologic imaging and to receive training on how to prepare their respective sites for participation in imaging trials that answer scientific questions ranging from cancer screening and early detection to therapeutic interventions and post-treatment surveillance.

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ECOG-ACRIN Cancer Research Group  |  Office of Communications
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