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Deep Dishing in Chicago
Accelerating neglected disease product development at the 2010 Partnering for Global Health meeting
It was a beautiful day overlooking Lake Michigan as 250 global health, biopharmaceutical, academic, and donor organization leaders gathered to dissect neglected disease product development and discuss how to increase investment in global health research and development.   The occasion was the 2010 Partnering for Global Health Forum, co-hosted by BIO Ventures for Global Health and the Biotechnology Industry Organization (BIO).
 
The day had many highlights.  The group heard from keynote speakers Dr. Regina Rabinovich, Director of Infectious Diseases at the Bill & Melinda Gates Foundation, and Dr. Nils Daulaire, Director of Global Health Affairs, U.S. Department of Health and Human Services.  Dr. Rabinovich set the tone for the day by describing her vision of a little girl who could grow up without the fear of death from a tropical disease.  "The Partnering for Global Health Forum has much to offer to make that vision a reality," she said. Dr. Daulaire used examples from his years of international development experience from the country to global level to outline how innovation and technology has made a difference and can be expanded upon to save many more lives in the future.
 
Jim Greenwood, President and CEO of BIO, was on hand in the morning to make a groundbreaking policy statement on how biotech companies can further contribute to improving access to medicines in the developing world.  He was joined by David Kappos, Under Secretary of Commerce for Intellectual Property and Director of the U.S. Patent and Trademark Office (USTPO), who called upon those gathered at the Forum to propose incentives to his office that would spur investment in global health.  "In the Obama administration, we are committed to these [access to medicines in the developing world] principles. We believe governments can, and will, provide incentives to help eliminate these diseases in developing countries," he said.
 
Dr. Hannah Kettler, Senior Program Officer at the Gates Foundation, led a boisterous panel discussion on the potential for various market-based incentives to make an impact on a biotech company's decision to invest in neglected disease product development.  The group unanimously agreed that more incentives are needed to encourage companies to invest in global health.
 
Gabriela Cezar, Venture Partner at Burrill & Company and a speaker on the emerging markets panel commented, "We are seeing a paradigm shift. Emerging markets are not only acting as absorbers and consumers of medicines, but are also having a more active role in being a source of innovation to fulfill those pipelines."  This was echoed by Dr. Mamphela Ramphele, Chair of the Technology Innovation Agency created by the South African government, who said that "without local partners, multinational companies cannot tap into the [emerging economy] markets."
 
The event preceded the BIO International Convention, which was in full swing Tuesday morning.  Partnering for Global Health attendees took part in more than 200 one-on-one partnering meetings at the BIO Business Forum, Tuesday through Thursday.    Eleven funding organizations, including Commons Capital, the International AIDS Vaccine Initiative, and the Bill & Melinda Gates Foundation gave presentations on their organization's strategic objectives.  A full list of presenting organizations is available on the Forum Web site: pgh.bio.org.
 
To learn more about this year's Forum, visit the BVGH Web site.
 
To view an archived webcast of the Forum, visit - http://pgh2010.dynamicwebcasting.net/.  Select 'Begin Webcast,' and then 'Open On Demand Panel Selection' at the bottom of the page.


 
Rx for Health
Jim Greenwood discusses BIO's groundbreaking policy statement on improving access to medicines in the developing world.
At the Partnering for Global Health Forum, Jim Greenwood, President and CEO of the Biotechnology Industry Organization (BIO), announced a groundbreaking policy statement on options for improving access to medicines in the developing world.   BIO Ventures for Global Health (BVGH) spoke with Rep. Greenwood, a BVGH board member, after the Forum to learn more about the principles and what BIO hopes they will achieve.

Q: BVGH is really pleased that BIO took the step to develop the Principles on Access to Medicines.  Can you tell me a little bit about how the decision to develop the principles came about?
 
A: BIO's member companies have been focused for a long time on strategies to make sure products are accessible to everyone who needs them.  In part, that was the motivation behind the creation of BVGH and the decision to spin it out of BIO into a separate entity focused on catalyzing relationships between disease-focused non-profits and our member companies. 

 
We are aware that in developing countries policy makers are forced into desperate efforts to get medicines to their citizens.  Unfortunately that manifests itself in what we think are negative policies like compulsory licensing or taking actions to weaken or mitigate intellectual property (IP) rights.  We firmly believe that IP rights facilitate access, rather than impede it, but unless we as an industry make greater efforts to address the access issue, our critics will continue to demand weakening IP rights around the globe.
 
Q: How were the principles determined?
 
A: We know that many of our member companies already have internal principles that guide them to make sure products get to the developing world.  We looked at existing practices among our companies and among universities, which are increasingly making these kinds of considerations as a critical part of licensing.
 
The principles were driven by our Board Standing Committee on IP who believe that BIO and the industry needed to be more proactive in addressing this issue. There are two reasons for this: one, it's the right thing to do, and two, the principles enable us to more effectively respond to those who believe that the source of access issues is strong IP rights.
 
Q: What do these principles mean for your member companies?  What are you hoping they will achieve?
 
A: The principles exist primarily to encourage companies that haven't thought about access to consider it and to take steps towards developing internal principles that make sense for their products.  It's a way of saying to companies that their industry trade organization thinks that this is a priority, and they should start to think in that way too.
 
We are also trying to encourage a race to the top. We want companies to compete and be exemplars to develop and act on principles that would make their products affordable and accessible to the developing world.
 
We are also hoping that companies will assist the non-profits and universities who are engaged in these types of issues.
 
Q: What was the significance of announcing the Principles at the Partnering for Global Health Forum (PGH)?
 
A: The audience at PGH is a gathering of some of the world's most committed people on the subject of making medicines available in the developing world.  It was important for us to take advantage of this kind of international stage to announce the principles.
 
We think the Forum attendees will be relying on and using these principles.  And we also hope that they will help us get the word out about the principles to ensure that access to medicines remains at the forefront of the discussion.
 
You can access the full Principles on Access to Medicines on BIO's Web site here: http://www.bio.org/healthcare/innovation/Access_to_Medicines_Policy_Statement_Final.pdf

Tracking R&D Investment for Neglected Diseases
The 2009 G-FINDER report surveys are out and BIO Ventures for Global Health would like to encourage biotech companies to complete the survey before June 4.
The G-FINDER report is produced annually by The George Institute for International Health and tracks annual investment in research and development for neglected diseases by the public and private sectors.   The goal of the report is to help funders better understand where the gaps are in neglected disease R&D and how their investments fit into the global picture.  The biopharmaceutical industry has ranked third among those funders over the past three years.  To learn more about the report and how to access it, visit our blog
Biotech Briefs
News of interest in global health, biotechnology, policy, academia, and finance.
Synthetic Genome Reboots Cell
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BusinessWire 19 May 2010
 
Abbott Receives FDA Approval for First Fully Automated Blood Test for "Kissing Bug" Disease
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Abbott 19 May 2010
 
Thousands of Possible New Drugs to Fight Malaria Identified
A team at GlaxoSmithKline's Tres Cantos Medicines Development Campus in Spain screened 2 million compounds in the GSK library for hits against Plasmodium falciparum, which led to more than 13,500 successful hits.  These hits could lead to the development of new malaria drugs.
Telegraph 20 May 2010

May 2010

BIO Ventures for Global Health is a non-profit organization whose mission is to save lives by accelerating the development of novel biotechnology-based drugs, vaccines, and diagnostics to address the unmet medical needs of the developing world.

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Board of Directors

Carl B. Feldbaum, Chairman
President Emeritus, BIO

Robert B. Chess
Chairman, Nektar Therapeutics

James A. Geraghty            Senior Vice President and Officer, Genzyme Corporation

James C. Greenwood
President, BIO

Donald R. Joseph               Chief Operating Officer, BVGH

Vaughn M. Kailian
General Partner, MPM Capital

Melinda Moree, PhD
CEO, BVGH

J. Leighton Read, MD
Partner, Alloy Ventures

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