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Speaking Up
Presenters at the Partnering for Global Health Forum voice critical debates about solving the unmet medical needs of the developing world.
In 1977, Dr. Mamphela Rampele -- a physician and anti-apartheid activist -- was banished by the South African government to the town of Tazneen for speaking out against the government.  She remained there until 1984.  Despite personal struggles, she emerged from the experience continuing her work in health care and eventually serving as one of the four managing directors of the World Bank.  Earlier this year, the South African government -- responsible for her internment only decades earlier --  named her the chair of the Technology Innovation Agency (TIA), a group that is tasked with developing the technology sector of the country's economy, with a particular focus on building the biopharmaceutical industry.
 
On Monday, May 3rd, Dr. Ramphele will join us at the 2010 Partnering for Global Health Forum to talk more about how the TIA intends to build the biopharmaceutical industry.  She is just one of the speakers at the Forum, representing a long list of panelists whose experiences will contribute to engaging and provocative discussions throughout the day.
 

The governments of India and China will also be present to explore how their countries are growing their domestic biopharmaceutical industries, as well as how they are working with foreign companies entering their markets.  Invitations are extended to both Dr. M.K. Bahn, Secretary of the Ministry of Biotechnology, Government of India, and Dr. Zhu Chen, Minister of Health, China, who have both indicated they will likely attend.

 

We have assembled a group of biopharmaceutical executives to debate incentives and analyze how different models could be the key in engaging more companies in neglected diseases. In a panel moderated by Hannah Kettler, Senior Program Officer at the Bill & Melinda Gates Foundation, the speakers, including George Scangos, CEO, Exelixis; Vijay Samant, CEO, Vical; and John Thomson, Vice President of Strategic R&D Networks, Vertex Pharmaceuticals will share with us their thoughts on what it takes to get companies involved in global health product development, given the current landscape and ever-evolving global markets.

 

Public/private partnerships will also be highlighted. During this session, panelists will compare effective business models and reveal how strategic partnerships can offer value that aligns with the partners' commercial strategies.  The first public/private partnership that will be discussed is aimed at the development of a new drug for Human African Trypanosomiasis and was featured in the BIO Ventures for Global Health publication Global Health Innovators: A Collection of Case Studies. It will feature David Perry, CEO, Anacor; Yves Ribeill, CEO, Scynexis; and Jean-Pierre Paccaud, Vice President of Business Development, Drugs for Neglected Diseases initiative.  Lisa Conte, CEO, Napo Pharmaceuticals, and Achin Gupta, Vice President of Corporate Strategy, Glenmark Pharmaceuticals will share information about a second public/private partnership.  This second partnership will be featured in an upcoming BIO Ventures for Global Health case study report.

 

At another panel, speakers Mark Feinberg, Vice President of Medical Affairs, Merck Vaccines; David Cook, COO, International AIDS Vaccine Initiative; Margaret Anderson, Executive Director, Faster Cures; and Paul Klingenstein, Managing Partner, Aberdare Ventures will discuss how neglected disease drug development traverses the "valley of death" despite the lack of commercial drivers that exist for developed world diseases.  

 

On Tuesday, May 4th, we'll move from a large scale meeting to one-on-one discussions in the BIO Business Forum, where executives will meet to discuss potential partnerships and how to begin to put the ideas of the previous day into action.  We will also hear from public sector funders on their organization's strategic priorities, including the Bill & Melinda Gates Foundation, PATH, and WHO TDR.  Funder presentations will take place between 2 and 5pm.  Visit the Partnering for Global Health Web site - pgh.bio.org - for a full list.

 

For more information -- including the full program -- or to register, please visit pgh.bio.org.


 
Bridging the Innovation Gap
BIO Ventures for Global Health COO Don Joseph discusses his commitment to solving the unmet medical needs of the developing world.

This week, BIO Ventures for Global Health announced that Don Joseph has been named Chief Operating Officer (COO) and a member of the Board of Directors.  Before joining BIO Ventures for Global Health, he served in senior executive positions in both legal and business roles at private and publicly held biopharmaceutical companies including Renovis and Abgenix, where he played a key role in its acquisition by Amgen.  He has consulted for a number of biopharmaceutical companies and previously served as COO of the Institute for OneWorld Health, a non-profit pharmaceutical company devoted to developing new and affordable medicines for neglected diseases.

 

We spoke with Don about this exciting news and what lies ahead for BIO Ventures for Global Health.


Q:  What made you decide to take on this role?
 

A: BIO Ventures for Global Health (BVGH) represents a unique opportunity to participate in addressing the global health needs of the developing world.  The biotech industry in particular, which is where I've spent much of my career, has a distinctive role to play in addressing those issues.  This is an exciting opportunity at the intersection of biotechnology, global health, cutting edge science, and policy.

 

On a personal note, in our travels in the developing world, my wife and I have always wanted our children to see how fortunate we are to live the way that we live and how many of the people in the world live a very different way.  My children inspire me to view the world as they do-without boundaries, borders, or limits to what we can accomplish. It's important to me to take the industry knowledge that I've gained over the years and point it in a different direction--to help the vast numbers of people who are not nearly as fortunate as we are in this part of the world.


Q: What do you think is unique about BVGH's role in the fight to solve the unmet medical problems of poor countries?
 
A: I don't know of any other organization that is bridging the innovation gap and facilitating relationships between the biopharma community and the needs of the developing world. The unique role that BVGH plays is to bring together the biopharma industry, with all of its advances, innovations, technologies, and creativity, and put that to work in the service of the rest of the world, which doesn't have access to these types of technology and information.  BVGH is well positioned with our staff, our management team, and our board of directors to communicate and speak the language of biopharma to global health, and vice versa.

Q: What do you see for the organization going forward?
 

A: As an organization, I would like to see us take the lead in creating new incentives -- new techniques that excite, motivate, and energize the biopharma community.  The Priority Review Voucher is one such program; the Advance Market Commitment is another. BVGH has played a leadership role in both areas.  Yet we still need more incentives and more creativity to free up the biopharma companies and motivate them to engage with us and engage with governments, NGOs, PDPs, and the others participating in global health. 

 

In five years, I hope to see that we have influenced and realized several of those new incentives.  Although we cannot accomplish this without the help of many stakeholders, we are in position to connect, communicate, and create. I am very proud to be a part of the unique contribution BVGH will make in bringing the world's best biotechnology to those who need it most.


Read Don's introductory blog here.


Biotech Briefs
News of interest in global health, biotechnology, policy, academia, and finance.
Researchers Race to Bring Cheap HIV Testing to Developing Countries
Responding to the need for new HIV diagnostics for the developing world, researchers at California company Palo Alto Research Center have shrunk the laser technology inside large laboratory machines down to about the size of an iPod. Their cheap, handheld device promises to provide an immune system check-up on the spot and in less than 10 minutes.

MinnPost.com 6 April 2010

Crucell, GSK Agree to Malaria Vaccine Development Deal

Dutch biotechnology firm Crucell said it had agreed with Britain's GlaxoSmithKline to jointly develop a malaria vaccine candidate. The deal is an extension to an earlier programme agreed in October 2003 between Crucell, GSK and the Walter Reed Army Institute of Research to evaluate Crucell's malaria vaccine candidate in pre-clinical studies.

Reuters 6 April 2010

Two Groups Push for Health Funds
The Global Alliance for Vaccines and Immunizations and the Global Fund to Fight AIDS, Tuberculosis and Malaria began this week to try to raise funding in the range of $24 billion from the Group of 20.
Wall Street Journal 29 March 2010

Pharmaceutical Firms, GAVI Alliance Agree to Provide Long-Term Supply of Pneumococcal Vaccine as Part of AMC
Millions of infants and young children in the world's poorest countries will receive potentially life-saving vaccines that help protect against pneumococcal disease, including pneumonia, thanks to agreements made with GlaxoSmithKline (GSK) and Pfizer Inc., the GAVI Alliance announced today. The supply agreements were made possible thanks to the Advance Market Commitment (AMC) for pneumococcal disease, an innovative financing mechanism piloted by the GAVI Alliance.
New-Medical.net 24 March 2010


April 2010

BIO Ventures for Global Health is a non-profit organization whose mission is to save lives by accelerating the development of novel biotechnology-based drugs, vaccines, and diagnostics to address the unmet medical needs of the developing world.

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Board of Directors

Carl B. Feldbaum, Chairman
President Emeritus, BIO

Robert B. Chess
Chairman, Nektar Therapeutics

James A. Geraghty            Senior Vice President and Officer, Genzyme Corporation

James C. Greenwood
President, BIO

Donald R. Joseph               Chief Operating Officer, BVGH

Vaughn M. Kailian
General Partner, MPM Capital

Melinda Moree, PhD
CEO, BVGH

J. Leighton Read, MD
Partner, Alloy Ventures

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