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BVGH Launches New Web Site
BIO Ventures for Global Health is excited to announce the debut of our new and improved Web site. We've listened to your feedback and updated our site for ease of use and given it a fresh new look.
The new site features important information on our projects and initiatives - like market based incentives, business model case studies, and the 2010 Partnering for Global Health Forum - to better inform you of our programs and the impact they are having on neglected diseases.  We are also excited about some new elements including a live version of our Global Health Primer - called the Neglected Disease Pipeline - which surveys the R&D landscape for 16 neglected diseases, our blog, and a news module with daily updates pertaining to global health R&D.

The address is the same: www.bvgh.org.  We hope you will stop by, explore, and sign up to stay informed about what we are doing.

The Power of Knowledge
BIO Ventures for Global Health to help innovative non-profits and academic research centers access the GlaxoSmithKline and Alnylam Pharmaceuticals Knowledge Pool
As the United States government prepared to enter World War I, the desperate need for aircrafts prompted pressure on the aircraft industry to form a patent pool to encourage rapid engineering innovation and manufacturing. This rather unusual arrangement was viewed as a critical step to encourage technological progress in an extreme threat to national security.  Although the intellectual property system was devised as a way to legally protect ideas and investments, as well as serve as an incentive to inspire innovation and promote scientific progress, individuals and companies sometimes decide to act to share intellectual property in times of need, and for the public good.
 
At BIO Ventures for Global Health, we believe in the power of intellectual property and what it can do to accelerate innovation, particularly for global health.That's why we recently announced that we are partnering with GlaxoSmithKline (GSK), and Alnylam to engage the global health community in using the powerful resources of the GSK and Alnylam Knowledge Pool. One year ago, the Knowledge Pool was announced as a result of GSK scientists' efforts to screen thousands of compounds for activity in 16 neglected tropical diseases. GSK identified and contributed over 500 granted patents and over 300 pending applications covering approximately 80 GSK patent families that cover small molecules and their formulations, uses, and processes for neglected tropical diseases. Alnylam then donated more than 1500 issued or pending patents on its RNA interference (RNAi) technology patent estate.
 
This is undoubtedly a vast resource for researchers; however, for many academic and global health non-profit groups, intellectual property can be perceived as preventing rather than enabling their work. The primary objective of the Knowledge Pool is to help those innovative non-profits and academic research centers working on developing products for neglected diseases to speed up their efforts by accessing the patents, technologies, and product development expertise available in the Knowledge Pool.  At BIO Ventures for Global Health, we are committed to using our new role as administrator of the Knowledge Pool to closing this cultural gap and ensuring maximum utility of the Pool's resources and expertise to benefit the public good.
 
To carry out this role, we are organizing disease-specific meetings that identify the gaps in expertise and intellectual property that currently exist in product development for neglected diseases. We will help global health researchers work with the resources of the Knowledge Pool to fill these gaps so that the resources generously made available by companies will be used to create medicines for neglected diseases faster and more efficiently. We are excited to accelerate the use of this important resource so that industry and global health researchers can work together toward the critical common goal of saving millions of lives in poor countries.
 
Stay tuned for updates as the disease-specific meetings move forward.
 
For more information, please see the press release on the GSK/Alnylam Knowledge Pool.


 
Partner Primer
TB Alliance CEO Mel Spigelman discusses what public sector attendees at the 2010 Partnering for Global Health Forum can expect from the BIO Business Forum.
The Partnering for Global Health Forum, co-organized by BIO Ventures for Global Health and the Biotechnology Industry Organization (BIO), kicks off May 3 and is co-located with the BIO International Convention in Chicago. Because of this co-location, non-profit attendees will have free access to the BIO Business Forum -- where thousands of one-on-one partnering meetings will take place from May 4-6 -- for the first time ever.  We spoke with Mel Spigelman, President and Chief Executive Officer of the Global Alliance for TB Drug Development (TB Alliance), about what public sector attendees can expect from the BIO Business Forum and how to get the most out of partnering meetings.

Q:  The TB Alliance has had several years of experience with partnering meetings generally and at the BIO Business Forum specifically.  Could you share some tips about how global health nonprofits can get the most out of these partnering meetings?
 
A: For the TB Alliance, the partnering meetings we participate in often serve as another point of contact with potential partners that we've already talked with.  In that sense, we view the BIO Business Forum as a part of the larger partnership process that goes from initial courtship to actually working together.  This isn't typically a one shot deal.  I saw that in a blog post, BIO Ventures for Global Health likened these partnering meetings to speed dating.  For some meetings, that is the case. You judge based on first impressions whether there is room to continue talks.  But to get the most out of these partnering meetings, it is important to do the initial research and legwork.  If you can walk into a first meeting with a potential partner with a common understanding, your conversation can progress much further.
 
One advantage of BIO's Business Forum is its sheer size.  As an organization, the TB Alliance contacts many potential partners through the year and it always becomes a question -- based on initial conversations -- whether it is worth meeting them in person.  The Business Forum at the BIO meeting allows that face-to-face time to happen easily.
 
Q: What advice would you give organizations that haven't experienced the partnering process before?
 
A: The biggest advice I would give is to do your homework.  You have to do the research beforehand and find organizations that -- based on their profile -- make sense for you to meet.  As a public sector organization, it is also important to make sure that you're promoting your own organization appropriately, and providing information about who you are and what you're trying to achieve. So much of what PDPs [Product Development Partnerships] and other global health players do is a foreign language to many biopharmaceutical companies.  The more information you can share prior to that half hour partnering session, the better.

Q: What is the TB Alliance's focus going into a meeting like this?
 
A: Traditionally, our focus at the BIO meeting is business development and the ability to further relationships we've established.  It is also a great opportunity to look into potential partnerships on the development side, research side, technology side, etc. What is intriguing about adding the Partnering for Global Health meeting is that you bring in other constituencies, beyond just the pharma and biotech crowd.  With governments and funders present, you create the possibility for a lot of other contacts. This should be of interest to the PDP world.
 
Q: So where do you see the greatest opportunity in this new mix, where we're bringing public sector participants, like PDPs, funders, and government representatives into the partnering space?
 
One of the problems that the PDPs have is that a lot of traditional public sector funders have left the research and development space to the private sector to fund.  Governments, for instance, have not typically funded what we consider the "valley of death" for global health drug development.  Development work has meant seeing the fruits of your labor immediately.  For instance, you can deploy bed nets, build a road, provide clean water, but this is not the case with research and development. Getting funding for research and development requires some education on the part of the funders. There really is a great value proposition for governments to invest in product development and not leave it to the private sector, particularly when you're talking about non-commercially viable products. You need longer-term perspectives and investments for bigger payoffs. The ability to educate along those lines is something that is a tremendous opportunity.
 
To learn more about the Partnering for Global Health Forum, visit pgh.bio.org.
Biotech Briefs
News of interest in global health, biotechnology, policy, academia, and finance.
Abu Dhabi Donates 25 Million Dollars to Fighting Malaria
The government of Abu Dhabi made a $25 million commitment to the Roll Back Malaria Partnership over five years to combat malaria.  It is hoped that this contribution will help make significant progress towards meeting the malaria-related United Nations Millenium Development Goals.
AFP 10 February 2010

Genes From Chagas Parasite Can Transfer to Humans and Be Passed On to Children
Brazilian scientists have shared new research that reveals that the parasite that causes Chagas disease - Trypanosome cruzi - can insert its DNA into part of the human genome and then be passed from parent to child.
ScienceBlogs 14 February 2010

Brazil Awaits Approval of Huge Science Budget
The Brazilian Ministry of Science and Technology is awaiting approval of a $3.6 billion budget it submitted to congress in December.  If approved in March, it will be almost 1/3 higher than last year's budget.
SciDevNet 11 February 2010

HIV, Malaria, Rabies, MRSA, and 30 Other Vaccine Targets in the 2010-2020 Pipeline
Bharat Book Bureau, a leading business information aggregator providing market research reports and online databases, recently released a report entitled 'What's Next in Vaccines?' which examines and estimates markets for a number of yet to be developed vaccines for chronic and infectious diseases.
PR Log 6 February 2010


February 2010

BIO Ventures for Global Health is a non-profit organization whose mission is to save lives by accelerating the development of novel biotechnology-based drugs, vaccines, and diagnostics to address the unmet medical needs of the developing world.

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Board of Directors

Carl B. Feldbaum, Chairman
President Emeritus, BIO

Robert B. Chess
Chairman, Nektar Therapeutics
James A. Geraghty            Senior Vice President and Officer, Genzyme Corporation

James C. Greenwood
President, BIO

Vaughn M. Kailian
General Partner, MPM Capital

Melinda Moree, PhD
CEO, BVGH

J. Leighton Read, MD
Partner, Alloy Ventures

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