Editor's Note: This is the second of a ten part series on Dr. Noe's "10 Steps to Optimal Health." See below for a recap of all 10 steps.

Webster defines a poison as "a substance that through its chemical action usually kills, injures, or impairs an organism; something destructive or harmful." By this definition, sugar and white flour both qualify as poisons, albeit mild ones.

Sugar and white flour increase the risk of high blood pressure, heart attack, stroke, obesity, diabetes, and high cholesterol. In addition, they may increase the risk of some cancers and most inflammatory diseases such as arthritis. They also suppress immune function, and in my experience, are one of the most common causes of fatigue, depression, anxiety, hypoglycemia, sugar or starch cravings, and intestinal yeast overgrowth (a possible cause of irritable bowel).

Most of these effects are due to the fact that sugar and white flour have a high glycemic index, which means that they spike your blood sugar. When your blood sugar spikes, your body secretes lots of insulin to bring your blood sugar back down. Unfortunately if this happens repeatedly the cells in your body can become resistant to insulin. It then takes a higher dose of insulin to have the same effect, so the body secretes more insulin. This eventually leads to greater insulin resistance, and so on. When someone has insulin resistance, they are at much higher risk of developing high blood pressure, high triglycerides (found on a cholesterol test), low HDL cholesterol (the good cholesterol), weight gain, and diabetes, among other things.

Even before insulin resistance occurs, many people who eat too much sugar or white flour will develop fatigue, weight gain, depression, anxiety, sugar cravings, and/or hypoglycemia (low blood sugar after eating).

Many people use honey or maple syrup as healthy alternatives to sugar. Unfortunately, honey and maple syrup also spike the blood sugar. While they may contain some vitamins, minerals, or enzymes that table sugar does not, these substances in no way counteract the negative effects of maple syrup and honey on blood sugar. Hence these foods carry most of the same risks and sugar.

Fruit, on the other hand, is a different story. Fruit contains a type of sugar that is absorbed and metabolized more slowly than the sugars found in other foods. Fruits are also high in fiber, which further slows the absorption of sugars. Most fruits therefore have a minimal impact on blood sugar, in addition to containing a wide array of antioxidants, bioflavonoids, and other substances that are very beneficial to your health. The sugar found in fruits is known as fructose, which should not be confused with high-fructose corn syrup (which is actually only 50% fructose and has dramatics impacts on blood sugar).

While there are lists available that show the glycemic index of individual foods, I don't recommend using them as they can be very confusing. Different labs get different results for slightly different foods, there are different scales (white bread vs. glucose), and different measurements (glycemic index vs. glycemic load). These lists also don't take into account other compounds found in foods that have beneficial impacts on health (such as the aforementioned bioflavonoids and antioxidants).

What is one to do, then? The simplest answer is to focus on eating lots of fruits, vegetables, healthy proteins, and whole grains. Examples of healthy proteins would include beans, nuts, soy, fish, dairy, eggs, poultry, and meat. It is a good idea to make sure that these protein foods don't have added sugar (such as flavored yogurt, baked beans, or sweetened soy milk). It is also a good idea to avoid excessive intake of saturated fats in dairy and meats and to try and get grass-fed dairy, poultry and meat (this reduces the saturated fat and increases the omega 3 fats in these foods).

A final caveat is that for people who are relatively healthy and aren't experiencing the symptoms or diseases listed at the beginning of this article, whole grains can be a healthy and enjoyable part of a balanced diet. For people with these complaints, however, further reducing even whole grains to 1-2 servings daily can often provide swift and dramatic relief from many of these conditions.

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Vitamin D May Boost Heart Failure Survival Rates

A study has found that heart failure patients with reduced levels of vitamin D have lower rates of survival than patients with normal vitamin D levels. As a result, researchers suggest that a low intake of vitamin D may be a factor in the development, and outcome, of heart failure. Vitamin D is produced by the skin when it is exposed to the natural ultra violet-B, or UV-B, radiation from the sun. Most tissues and cells have a vitamin D receptor; and evidence suggests vitamin D reduces the risks of several chronic illnesses such as common cancers, autoimmune diseases, kidney diseases, chronic infectious diseases, high blood pressure - and apparently, heart failure. The study team described the evidence of a protective effect from vitamin D as "compelling," and recommended that heart failure patients should be advised to take vitamin D supplements and eat oily fish or eggs. The study was presented August 31, 2010 at the annual congress of the European Society Cardiology. It has not yet been published in a peer-reviewed journal.

Fish Oils Fight Inflammation and Diabetes

Finally, a study has identified the mechanism by which omega-3 fatty acids appear to effectively fight chronic inflammation, insulin resistance and diabetes. The study found that there is a key receptor in obese body fat and that omega-3 oils - specifically docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) - activate this receptor, which results in broad anti-inflammatory effects and improved systemic insulin sensitivity. (There is a strong connection between obesity and diabetes.) The effect of fish oil was powerful, according to the researchers, and, "The omega-3 fatty acids switch on the receptor, killing the inflammatory response." The study team warned that more study is required to determine how much fish oil constitutes a safe and effective dose. Researchers suggested that the study could eventually lead to a natural dietary remedy for the more than 23 million Americans who suffer from diabetes. This study was published in the Friday, September 3, 2010 issue of the journal, Cell. The full-text version is now available online without fee at http://bit.ly/9TQ09d.

Kidney Problems Linked to Vitamin C Deficiency

A study has found that kidney dysfunction is associated with a low blood level of vitamin C. Also, low blood levels of vitamin C may cause damage, from greater oxidative stress, among kidney disease patients. It was noted that diabetic patients had consistently reduced levels of vitamin C. Lower blood levels of vitamin C have previously been linked to a greater risk of death from cardiovascular disease. People with higher levels of vitamin C have been found to have a reduced risk of cardiovascular disease and to have a greater life expectancy. (Vitamin C is an essential nutrient in humans and acts as an antioxidant, protecting the body against oxidative stress. Most species can synthesize vitamin C but humans cannot.) A brief summary of this study was released September 3, 2010 by the journal, Nephrology Dialysis Transplantation but the study will not be published in the print journal until a future issue. The full-text version is currently available online, for subscribers and those who pay the article access fee, at http://bit.ly/bPgeer.

Low Levels of Vitamin D Linked to Double the Risk of Schizophrenia

Babies with low levels of vitamin D have an increased risk - in fact, double the risk - of developing schizophrenia later in life. That's the conclusion of a new study of 424 individuals that showed a link between vitamin D (25 hydroxyvitamin D3) sufficiency and healthy brain growth. (Vitamin D is produced by the effect of sunshine on the skin and, although linked to bone health, researchers have previously found that people with schizophrenia are more likely to be born in winter, when sunlight is rare.) "Improving vitamin D levels in pregnant women and newborn babies could reduce the risk of later schizophrenia," said one of the researchers. It's important to note that a link between schizophrenia was found with both insufficient and excess levels of vitamin D. The team described as "urgent," the need for further study to assess best levels of vitamin D. This study was published September 7, 2010 in the Archives of General Psychiatry. The full text of the study is available online now at http://bit.ly/aIcjQp for journal subscribers and those who pay the article access fee.

Poor Dental Hygiene Linked to Heart Disease

A study suggests that without proper brushing of teeth and regular flossing, bacteria from plaque can escape into the bloodstream, where they can initiate blood clots and generally wreak havoc on the body. Researchers stressed that people need to maintain good dental hygiene to help ward off blood clots and heart disease in general. The study showed that, once in the bloodstream, Streptococcus bacteria make blood platelets bind together and completely encase the bacteria, protecting the bacteria from the body's immune system and from antibacterial drugs. This creates small clots, growths on the heart valves, or inflammation of the blood vessels. This study was released September 9, 2010 at the autumn meeting of the Society for General Microbiology in Nottingham, UK. However, it has not yet been published in a peer-reviewed journal and is not yet available online.

Vitamin B Supplements Could Halt Alzheimer's Progression

A study has found that supplementing the diet with large doses of vitamin B could cut, by a third to a half, the brain shrinkage that is common in elderly people with early signs of the disease and could slow, or even halt, the memory-robbing disease's progression. The researchers stressed the need for further study to confirm these results but described the study outcome as "striking" and "dramatic." Over a two-year period, half of the168 volunteers, all of whom were over the age of 70 and had been diagnosed with mild cognitive impairment (MCI), were given high daily doses of the B vitamins folate, B6 and B12, higher doses than normally found in supplements or diet. "Participants were randomly assigned to two groups of equal size, one treated with folic acid (0.8 mg/d), vitamin B12 (0.5 mg/d) and vitamin B6 (20 mg/d), the other with placebo." On average, compared to the group that received only placebo pills with no active ingredients, B-taking volunteers exhibited an average 30 percent lower degree of brain shrinkage, which is associated with atrophy; but in some cases, the reduced amount of atrophy was lower by as much as fifty percent. The study was released September 8, 2010 by the online journal Public Library of Science ONE and can be accessed free online at: http://bit.ly/btsJCl.

Sorghum Found To Be Antioxidant-Rich - Even Richer Than Blueberries

A study has concluded that sorghum bran contains greater antioxidant content and anti-inflammatory power than known antioxidant-rich superstars, such as blueberries and pomegranates. Researchers tested four varieties of sorghum and found that the two with the highest tannin composition - the black and sumac sorghum varieties - contain a whopping 23 to 62 mg of polyphenolic compounds per gram compared to antioxidant-rich blueberries, which contain 5 mg per gram, or pomegranate juice, which contains 2 to 3.5 mg per gram. Many fruits also contain antioxidants but sorghum bran, suggested the researchers, may prove to be the very richest and cheapest source. High-antioxidant berries and fruits are among the most expensive. Low tannin sorghum is commonly fed to animals or used to make ethanol to fuel cars. Only recently, has high-tannin sorghum bran been added to a few food items; the study team hopes to interest manufacturers in adding the low-cost, high-tannin extract to foods and beverages in order to prevent disease "rather than promote it." In addition to antioxidants, sorghum also contains fiber. This study was published in the August 2010 issue of the Journal of Medicinal Food. The full-text version of this study is available online at http://bit.ly/cQPqCd with journal subscription or article access fee payment.

Selenium Supplements May Decrease Risk of Bladder Cancer

A study has found that a higher intake of selenium may lower the risk of bladder cancer. Researchers analyzed several previous studies and examined selenium content in toenails and blood and compared these measurements with the incidence of bladder cancer. Although there was a general protective effect for selenium levels, women benefited most in terms of bladder cancer risk. (Selenium is found in plant foods grown in selenium-rich soils, in the meat of animals that grazed on selenium-rich soils, and in selenium supplements. It is an essential micronutrient that is incorporated into about 25 proteins, called selenoproteins, which prevent cellular damage caused by the by-products of oxygen metabolism.) Further study is required to confirm these results and to determine the optimum dose of selenium to provide a protective effect against bladder cancer. This study was released August 31 and published in the September 2010 issue of the journal, Cancer Epidemiology, Biomarkers & Prevention. The full-text version is now available online with a journal subscription or payment of an article access fee at http://bit.ly/cImcWJ.

Watercress May "Turn Off" Breast Cancer

A study has found that a compound in watercress may have the power to suppress breast cancer cell development. Normally, as cancer cells develop, they send out signals that cause new blood vessels to grow into the tumor and these nourish the rapidly growing cancer cells with oxygen and nutrients. But a watercress compound - called phenylethyl isothiocyanate - appears to turn off the tumor signal within the body, effectively starving the breast cancer cells. The amount of watercress consumed by test subjects was 80gm, which is about a cereal bowl full. (This leaf vegetable is known for its tangy, peppery flavor and is a member of the Brassica or cruciferous family, which includes cabbage and broccoli. Previously, watercress has been linked to a lower risk of lung cancer and of low thyroid levels.) The study leader suggested more research is needed on the relation between what we eat and cancer. This study was presented at a September 14, 2010 press conference and will be published in the current issue of the British Journal of Nutrition.

Anxiety Meds Raise Mortality Risk

A 12-year study of 14,000 patients has found that patients who take medications to treat insomnia and anxiety, even on an irregular schedule, have a 36 percent greater risk of dying than those who do not. This is considered a small but significant increase in risk. What causes this higher risk of mortality among those taking drugs to treat insomnia and anxiety is not clear but researchers pointed out that these prescriptions affect reaction time, alertness and coordination, making patients subject to falls and accidents. Also, patients on these meds are more prone to breathing problems during sleep; and some drugs of this type increase the risk of suicidal behaviors. The team leader suggested that non-drug cognitive behavioral therapies have been shown to be effective against both insomnia and anxiety and that this type of therapy should be suggested to patients. Also, according to the head researcher, "These medications aren't candy, and taking them is far from harmless." This study was published in the September 2010 issue of the Canadian Journal of Psychiatry and is available online now in its full-text format at: http://bit.ly/964IPZ.

Special Diet Prevents Kidney Stones

A study has found that the DASH diet, a diet designed to combat high blood pressure and also known as Dietary Approaches to Stop Hypertension, also helps prevent kidney stones. This diet is high in fruits, vegetables, nuts and legumes, dairy products, and whole grains, and low in sweetened beverages and red and processed meats. Despite similar fluid intakes, the study observed a greater output of urine among those on the DASH diet, which may stem partly from the fact that DASH foods have higher water content. More important, DASH subjects' urine held higher concentrations of citrate, an important inhibitor of calcium kidney stones. Researchers suggested that two foods prominent in the DASH diet have potent kidney stone-fighting properties: low-fat dairy products and plant foods. This just-released study will be published in the October 2010 issue of the journal, Clinical Journal of the American Society of Nephrology. It is now available online at http://bit.ly/aZu1yY with subscription to the journal or payment of an article access fee.

Multivitamin Use May Prevent Heart Attacks in Women

A study of 31,671 women has found that, compared to taking no supplements at all, regular daily use of multivitamins over a minimum ten-year period reduced the incidence of myocardial infarction (heart attack), at least among those women who had no history of cardiovascular disease (CVD) at the start of the study. There was no similar benefit for women who had a history of CVD. But among those with no CVD history, supplements other than multivitamins had little effect on heart attack risk; multivitamins alone reduced heart attack risk by 27 percent; and multivitamins taken with other supplements lowered heart attack risk by 30 percent. Multivitamins were estimated generally to contain close to the recommended allowances for vitamins A, C, D, and E, thiamine, riboflavin, vitamin B6, vitamin B12 and folic acid. The relationship is not necessarily one of cause-and-effect and further study is needed on the exact contents of multivitamins, the required duration of use, and the reason that supplements had no heart benefit for women with CVD. This study was released September 22, 2010 and will be published in a future issue of the American Journal of Clinical Nutrition. It can be read online in the meantime at http://bit.ly/a1wmNr with journal subscription or payment of an article access fee.

MS Symptoms Eased By 'Mindfulness Meditation'

A study has determined that learning mindfulness meditation can help Multiple Sclerosis (MS) patients with the fatigue, depression and other life challenges that usually accompany the disease. The effect lasted for six months. For the study, 150 MS patients were assigned either to regular medical care alone or to medical care plus weekly classes lasting two and a half hours; the classes included mental and physical exercises aimed at developing nonjudgmental awareness of the present moment, or "mindfulness." Those who went through the mindfulness training were far better able to cope with fatigue and depression; in fact, mindfulness helped reduce depressive symptoms by over 30 percent. Mindfulness is a concept that might be described as "calm awareness of one's body functions, feelings, content of consciousness, or consciousness itself." This study was the largest of its type and is considered to have been well-conducted. The study was published in the September 28, 2010 issue of the journal, Neurology, and is now available online at http://bit.ly/dgV6cb with journal subscription or payment of an article access fee.

Strong Link between Air Pollution and Diabetes

A study has found a strong link between particulate air pollution and adult diabetes; and between pollution and inflammation, which may contribute to insulin resistance, which in turn is linked to diabetes. The study focused on a particular size of fine particulates in air pollution (0.1 to 2.5 nanometers in size), the same size associated with a key component of haze, smoke and motor vehicle exhaust. Researchers adjusted the data to rule out the effects of known diabetes risk factors, including obesity, exercise, geographic latitude, ethnicity and population density. But there was still a very strong correlation between air pollution and the incidence of diabetes. The study team did not point to air pollution as necessarily being a cause of diabetes but it came across as a valid predictor of the disease. Even within counties falling within the Environmental Protection Agency (EPA) limits for air pollution exposure, those with the highest levels of exposure were 20 percent more likely to develop diabetes. The team suggested EPA standards may not be adequate to protect people from pollution. Released September 29, this study will be published in the October 2010 issue of Diabetes Care. It is online now at http://bit.ly/dqTEPB without charge.

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