| NanoImaging Services is exclusively focused on reliable and accurate nanoparticle characterization methods using TEM for the pharmaceutical and biotechnology industry. Please take a minute to see how NanoImaging Services can help you and your research. |
|
Cryo-transmission electron microscopy image of liposomal encapsulated doxorubicin sample.
|
Electron
tomography provides three-dimensional structural information of
nanoparticles such as viruses, liposomes, or protein complexes. The
method computationally reconstructs a 3D volume of the sample by
combining a series of images obtained as the sample is rotated by fixed
angles in the microscope. Electron tomography provides an additional
dimension useful for assessing the 3D morphology of particles and
sample aggregation.
A Youtube movie showing electron tomography of the liposomal doxorubicin sample may be seen at http://www.youtube.com/watch?v=zu--EipZ7Yo
|
| NanoImaging Services specializes in using transmission electron microscopy for direct visualization of nanoscale samples in solution, such as: proteins & protein complexes, liposomes & emulsions, viruses & virus like particles, and other nanoscale particles. The company specializes in cryoTEM methods, which preserve samples in their native fully-hydrated state. NanoImaging Services provides critical information to help determine morphology characterization, particle assembly assessment, aggregation states, and 3D structure for your samples. These data are useful throughout all stages of the drug development cycle, including: drug discovery, characterization during scale-up, regulatory review, validation and lot-to-lot comparisons. |
Nanoimaging Services has received a Small Business Innovation Research (SBIR) grant from the National Institutes of Health through the National Center for Research Resources to develop new methods for quantitative characterization of nanoparticle morphology and aggregation state using transmission electron microscopy. Lean more... |
NanoImaging Services provided the CryoTEM analysis for an investigation of Polymeric Micelles for parenteral delivery of Sagopilone by Annett Richter and collegues at Bayer Schering Pharma AG. The work is described in the International Journal of Pharmaceutics. Learn more...
|
NanoImaging Services will be attending these upcoming meetings:
AAPS National Biotechnology Conference, May 16-19, San Francisco
Particles 2010, May 22-25, Lake Buena Vista, FL
Vaccine Technology III, June 6-11, Nuevo Vallarta, Nayarit, Mexico
Controlled Release Society, July 10-14, Portland, OR
Please contact us if you'd like to schedule a time to meet with us.
|
Contact Information:
NanoImaging Services
10931 North Torrey Pines Rd., #108
San Diego, CA 92037
Ph: 888-675-8261
email: info@nanoimagingservices.com
website: www.nanoimagingservices.com
 |
