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Patient News 

 

Annual Patient Workshop

 

Save the date:

Sunday

 February 17, 2013

 

Hilton Dallas-Fort Worth Lakes Executive Conference Center 

 

 

Therapy Tip

 

Chronic Illness Recovery recommends that patients on

Inflammation Therapy maintain a level of 25-D between 8-15 ng/ml because this level ensures adequate stores of 25-D and isn't so high as to promote elevated levels of 1,25-D. However, if doctors want their patient's 25-D to be maintained between 20-24ng/ml, that is acceptable -

it won't interfere

with immune system

function during the recovery process.

 

 

Recovery Reports

 

We are contacted daily by people with chronic illnesses who are looking for an effective treatment. Many ask us to provide evidence of efficacy in the form of statistics or stories. If you have recovered your health or had significant symptom improvement with Inflammation Therapy (or a similar treatment), please help us 'pay it forward' by telling your story. We will post it in the public section of our website to encourage others. Any report, short or long, with or without objective data (e.g., lab results, imaging reports) would be helpful. Please

send your story to

our email .

Thank you!  

To see the latest recovery reports,

click here. 

 

CIR Library Access

 

Access to our free, extensive, easy-to-read Library of Information

 (see this sample page)

and Physicians' Reference Library is available to anyone, without enrollment in our counseling program. If you're interested in using this resource, please send a request to our email

 address along with your doctor's name and fax number (in the US or Canada) or his/her email address, so we can notify your doctor that you have access to this information.

A list of the articles in our libraries is available at this link.

 Physicians may use CIR libraries even if they don't have a patient enrolled in our counseling program. Interested medical practitioners should contact CIR and ask to register.

 

Survey

 

Volunteers who have a diagnosis of autoimmune or inflammatory disease or are chronically ill but who are not being treated with Inflammation Therapy, the Marshall Protocol or the Stillpoint Protocol are needed to be in the control group of our clinical study. If you meet these criteria and would like to take part in this project (which will only take a few minutes

each month), please 

contact us at our  

email address.

 

  

 

 CIR is an IRS-recognized 501(c)3 non-profit charitable organization. 

Donate to CIR

 in support of our educational and research efforts. 

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you may phone us toll free from anywhere in the US and Canada
1-888-846-2474
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Chronic.Illness.Recovery
 
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Have you enjoyed this newsletter?

  

 

 

 

  

HONcode 

  

The Internet has become an important communication tool but it isn't always easy to tell which information is reliable. When it comes to your health, it's important to be sure you're accessing a credible source. Health On the Net Foundation has certified that the Chronic Illness Recovery website and forum conform to the principles of the HONcode for the dissemination of trustworthy health information for patients and professionals. The HON seal on our website is your assurance that we're providing medical information

you can trust.

Click here

 for details.

 

 

Issue: 34
September 2012
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Greetings!

   

Chronic Illness Recovery's mission is to promote and support recovery from chronic illness through physician services, patient counseling, informational materials, seminars, research and participation in public health policy design.

 

We hope you've had a chance to be instrumental in our efforts to inform physicians about this effective treatment. It's easy to do - just enroll in our counseling program. You get the benefit of professional counseling and your doctor learns how to manage Inflammation Therapy. You'll be helping to increase awareness of treatment efficacy which may spark an interest in the research community so the resources to conduct clinical studies will become available.

 

Please share this newsletter with others and give us your feedback so we know what you like and what you would like to see in the future.

 

Best wishes,

 

signature            Belinda 

About Inflammation Therapy 

 
Vitamin D and Osteoporosis

 

stoopingMany chronic diseases are associated with a higher risk of osteoporosis or osteopenia. Osteoporosis literally means "porous bones." Osteoporosis is characterized by the gradual loss of bone mass, causing the bones to become thinner, fragile and more likely to break. Osteopenia describes a lack of calcification in bones. It's the term used to describe bones that are losing mineralization, but not as significantly as in osteoporosis. Bone consists of both non-living substances (minerals) and living tissue (blood vessels, nerves, collagen, and cells). Osteoclasts (bone dissolvers) are specialized cells that resorb (dissolve) old bone cells. Osteoblasts (bone builders) are specialized cells that lay down new bone cells.

Because the thickness and strength of bone must be maintained, bone remodeling (old bone replaced by new bone) is a continuously ongoing process. If the two processes are in balance, then bones are normal. But, if osteoclasts outnumber osteoblasts or if they're working faster than osteoblasts, then existing bone is resorbed faster than new bone can be laid down, and bone loss results.

Factors that can upset the normal balance between bone resorption and bone formation include hormonal imbalances and the lack of nutrients/minerals necessary for forming bone.

Collagen fibers and calcium salts help to strengthen bone. It's commonly thought that vitamin D is necessary for the proper absorption of calcium in the small intestine and doctors may be concerned that patients will develop osteoporosis if their 25-hydroxyvitamin-D (25-D) is maintained at the recommended 8-15 ng/ml during Inflammation Therapy.

However, the Vitamin D Receptor (VDR) transcribes the genes which are the key to shuttling calcium through the epithelium. [1.]  [2.]

Thus, it's not vitamin D which causes absorption of calcium from the gut, it's a competent VDR. We theorize that the VDR is disabled by inflammatory processes when L-form bacteria parasitize the cells, causing dysregulated vitamin D metabolism and excess production of the hormone 1,25-dihydroxyvitamin-D (1,25-D).

 

matrixElevated 1,25-D induces increased production of osteoclasts from stem cells. [3.] At levels above 42 pg/ml, 1,25-D causes bone resorption and puts patients at risk for osteoporosis.[4.]

The Danish epidemiologist Brot studied 500 healthy women aged 42 to 58 and concluded that "elevated levels of 1,25-(OH)2D were associated with decreased bone mineral density and content, reduced calcium: phosphorus ratio in the diet and increased bone turnover". [5.] When nutritional calcium is not absorbed, the body resorts to taking calcium from bones to maintain normal serum calcium levels. [6.] If 1,25-D remains elevated, osteoclasts will continue to dissolve bone and the excess calcium may be deposited in soft tissues, including lungs, breasts, muscle bundles (fibromyalgia) and kidneys (kidney stones).

Supplementing with vitamin D in an effort to increase bone density is futile and may be harmful because it can increase the production of 1,25-D. The Lancet and the British Medical Journal published studies showing that vitamin D supplementation dose not strengthen bones. [7.]  [8.]

This August 2008 study concluded, "In patients with a baseline calcium intake of 1100 mg/d and vitamin D insufficiency, vitamin D(2) 1000 IU for 1 year has no extra beneficial effect on bone structure, bone formation markers, or intestinal calcium absorption over an additional 1000 mg of calcium. Vitamin D supplementation adds no extra short-term skeletal benefit to calcium citrate supplementation even in women with vitamin D insufficiency." [9.] In summary, it's the disease process (Th1/Th17 inflammation) that causes a calcium deficit which results in osteopenia and osteoporosis. A lack of dietary vitamin D does not cause bone loss; whereas a high level of 1,25-D does. Inflammation Therapy will reduce 1,25-D and result in a better balance between bone formation and bone breakdown.

  

1. Estrogen receptor-beta modulates synthesis of bone matrix proteins in human osteoblast-like MG63 cells. 
 

2. Platelet vitamin D receptor is reduced in osteoporotic patients. 

 

3. Importance of Vitamin D receptor for neuronal control of hematopoietic stem cell niche. 

 

4. Vitamin D antagonist, TEI-9647, inhibits osteoclast formation induced by 1alpha,25-dihydroxyvitamin D3 from pagetic bone marrow cells.

 

5. Relationship between bone mineral density, serum vitamin D metabolites and calcium: phosphorus intake in healthy perimenopausal women.

 

6. Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization.

 

7. Vitamin D and Calcium Supplements for Elderly a Waste of Time

 

8.Randomized controlled trial of calcium and supplementation with cholecalciferol (vitamin D3) for prevention of fractures in primary care. 

 

9. Randomized controlled trial of the effects of calcium with or without vitamin D on bone structure and bone-related chemistry in elderly women with vitamin D insufficiency.

 

 

Scientific Articles

  

Inflammatory disease can increase bone resorption, decrease bone formation but most commonly impacts on both of these processes resulting in an uncoupling of bone formation from resorption in favour of excess resorption.

Bone Loss in Inflammatory Disorders

 

The preference toward bone resorption or formation/repair appears to be influenced by the inflammatory microenvironment.

The Flip Side of Osteoimmunity: Crosstalk Among Stem Cell, BMP-2 and Innate Immune Cells, and the Control of Osteoblastogenesis

 

Among older community-dwelling women, annual oral administration of high-dose cholecalciferol resulted in an increased risk of falls and fractures.

Annual High-Dose Oral Vitamin D and Falls and Fractures in Older Women: A Randomized Controlled Trial 

 

About CIR

  

Due to public demand for accurate information about inflammation therapy, over 40 of the articles from our private Library of information have been edited and are now available as a resource for patients researching treatment options. They can be found in an index by clicking the About Inflammation Therapy link in the navigation menu at www.chronicillnessrecovery.org.


You may find the following particularly helpful:

Simple Introduction to Inflammation Therapy

Overview of Inflammation Therapy

Efficacy and Expectations of Inflammation Therapy

Intracellular Bacteria

Vitamin D

Benicar (Olmetec)

 

Quotes 

   

"Interesting that each time I have had a bone density test done since starting on this treatment, my bone density has slightly improved yet vitamin D concentrations in my body remain low." Pundun

 

"I like your website because you are open about where IT sits in mainstream medical thinking, and about not hesitating to go for other help if serious reaction etc. You are clear about risks and other things on your disclaimer page. You try to educate people and provide links to reputable papers, and encourage open discussion. Congratulations on an awesome website." BarbP

 

"1 1/2 years ago, I had almost resolved myself to the fact that I would, at the age of 50, be in a wheelchair and have to live in assisted living for the rest of my life. Now, I work out 6 days a week in a very strenuous Aqua Fit class and I cruised to Alaska where I went dog sledding and sea kayaking. Amazing!" Sue

 

"I like it that things seem to be pro experimenting here in order to learn about everyone's individual reactions." Hexnut

  

 

 

Understanding Vitamin D video 

 

...bones and so much more... 

  bone