|Season's greetings to our entire community- our depositors,
requesters, board of directors, collaborators, employees, friends, and family- and best wishes for the New Year!
Q&A with Dr. Adam Bogdanove
Dr. Adam Bogdanove is a professor at Iowa State University and is a co-creator of the Golden Gate TALEN and TAL Effector Kit , along with Dr. Daniel Voytas form the University of Minnesota.
Q: Thinking long term, do you see TAL effectors as a potential tool in gene therapy?
A: Yes absolutely. I think that is one area in which they hold great promise. Imagine being able to sidestep all the complications of transplanting healthy stem cells from a donor (immune rejections, etc) and instead engineering ("fixing") cells from the patient and reintroducing them.
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Hot Papers and Plasmids
- Genetically Engineered Ca2+ Indicators (GECOs)
- TFs for reprogramming of fibroblasts into motor neurons (iMNs)
- Zinc Fingers in Zebrafish
- Multicistronic Expression in Drosophila
A TALe to Remember
by Eric J Perkins
Imagine being able to manipulate a specific region of DNA in the genome of your favorite species almost as easily as correcting a typo in the latest draft of your dissertation. Well, that will probably never happen. Yet with transcription activator-like (TAL) effectors, scientists in several biological disciplines are coming closer to this DNA targeting ideal.
Learn more about TALes in this month's technology feature.
Holiday Gift Guide 2011
It's the most wonderful time of the year
It's the hap-happiest season of all
There'll be seminars for hosting
Grad students for roasting
And traffic out in the snow
There'll be scary grant deadlines
And tales of the glory of
Funding long, long ago
Need some inspiration this holiday season? Try our last-minute gift guide- sure to put a smile on your face!
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