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American Health News and
Wellness Report Newsletter
Prevention is a Cure (c) FEBRUARY 2012- Vol 13 Issue 49 |
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Greetings! |
Calendar of events
Saturday, February 4th. 2012 9 am to 10:30 am
Senior Friendship Club: A discussion group
Heritage Park West Library
5859 Via Flora, Delray Beach
561 361 9091 $1 donation to the charity
Monday,February 6th. 2012 7:30 pm
The Boca Poetry Society
Boca Raton Community Center
150 Crawford Blvd, Boca Raton
561 361 9091 Free
President American Health Association J. Robert Gordon
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| Halting esophageal cancer in its tracks with sugar |
Halting Esophageal Cancer in its Tracks with Sugar
Scientists working at the Medical Research Council have identified changes in the patterns of sugar molecules that line pre-cancerous cells in the esophagus, a condition called Barrett's dysplasia, making it much easier to detect and remove these cells before they develop into esophageal cancer.
Esophageal cancer is the fifth biggest cause of cancer death in the United Kingdom and the eighth leading cause of cancer deaths for men in the United States. Moreover, the number of people diagnosed with this disease is increasing rapidly. Individuals with a pre-cancerous condition known as Barrett's esophagus are at an increased risk of developing esophageal cancer, and need to be closely monitored to make sure that the disease is not progressing.
Dysplasia offers a stage at which cancer can be prevented by removing these cells. However correctly identifying these areas has proved to be problematic, as they can easily be missed during endoscopy and biopsy, which only take samples from a small part of the esophagus. This can result in false reassurance for patients in whom their dysplasia has been missed, and conversely those without dysplasia having to undergo further unnecessary treatments.
The team, based at the MRC Cancer Cell Unit in Cambridge, was led by Dr. Rebecca Fitzgerald and included New York University's Lara Mahal, an associate professor of chemistry, and William Eng, a laboratory technician.
The researchers discovered a new mechanism for identifying Barrett's dysplasia cells by spraying on a fluorescent probe that sticks to sugars and lights up any abnormal areas during endoscopy. By analyzing the sugars present in human tissue samples taken from different stages on the pathway to cancer-using microarray technology developed by NYU's Mahal-they found that there were different sugar molecules present on the surface of the pre-cancerous cells. This technology uses sugar binding proteins, known as lectins, to identify changes in sugars and pinpointed carbohydrate binding wheat germ proteins as a potential diagnostic. When the wheat germ proteins, attached to a fluorescent tag that glows under a specific type of light, were sprayed onto tissue samples, it showed decreased binding in areas of dysplasia, and these cells were clearly marked compared with the glowing green background.
"The rise in cases of esophageal cancer both in the UK and throughout the Western world means that it is increasingly important to find ways of detecting it as early as possible," Fitzgerald was quoted as saying.
"Our work has many potential benefits for those with Barrett's esophagus who have an increased risk of developing esophageal cancer."
"We have demonstrated that binding of a wheat germ protein, which is cheap and non-toxic, can identify differences in surface sugars on pre-cancerous cells," she added.
"And when coupled with fluorescence imaging using an endoscopic camera, this technique offers a promising new way of finding and then treating patients with the highest risk of developing esophageal cancer, at the earliest stage."
SOURCE: Nature Medicine, January 2012 |
| Expensive egos and narcissism |
Expensive Egos & Narcissism
(American Health Newswire) -- Narcissism is a personality trait that is defined by an inflated sense of grandiosity, self-importance, and overestimations of uniqueness. A University of Michigan psychologist, Sara Konrath, was quoted as saying in a recent study published in PLoS One, "Narcissistic men may be paying a high price in terms of their physical health, in addition to the psychological cost to their relationships." The study shows that the level of narcissism is rising in the United States and tends to be more prevalent in men.
One hundred and six undergraduate students were examined by Sara Konrath, David Reinhard of the University of Virginia, William Lopez and Heather Cameron of the University of Michigan. They measured the students' levels of cortisol, a marker of physiological stress, based on the role of narcissism and sex. They measured the levels of cortisol through gathered samples of salvia at two points in time to assess a base. They were not allowed to be stressed at the time. If levels were elevated at a non-stressful state of mind, then the result would be chronic hypothalamic-pituitary-adrenal axis (HPA) activation and would increase the risk of cardiovascular problems.
The researchers had to assess students' narcissism by administering a 40 question survey that measures five personality trait components: exploitativeness, entitlement (more unhealthy), leadership/authority, superiority/arrogance, and self-absorption/self-admiration (the more adaptive or healthy components). They found that higher cortisol levels and the more dangerous aspects of narcissism were associated in males, but not females.
"Even though narcissists have grandiose self-perceptions, they also have fragile views of themselves, and often resort to defensive strategies like aggression when their sense of superiority is threatened. These kinds of coping strategies are linked with increased cardiovascular reactivity to stress and higher blood pressure, so it makes sense that higher levels of maladaptive narcissism would contribute to highly reactive stress response systems and chronically elevated levels of stress," David Reinhard was quoted as saying,
SOURCE: PLoS One, January 2012
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| Treating tremors with an ultrasound |
Treating Tremors With An Ultrasound
BALTIMORE (American Health Newswire) --Millions of Americans suffer from tremors. Patients with constant shaking can have trouble with some of life's everyday activities. Things like eating and drinking or holding a pen to write, are almost impossible. Now, learn about a breakthrough procedure that could help some patients get a steady hand.
"My hand shook constantly, as it's shaking now, it would never stop," Billy Williams, a tremor patient told American Health.
For the past 10 years, Billy Williams suffered from a tremor in his hand.
"Constantly, it never, never quit," Williams said.
No one knows why he shakes, but the tremor was so bad, Billy stopped eating out in public and his writing became illegible.
"I had trouble writing my name, I couldn't sign anything," Williams explained.
Now, neurosurgeons are using a new procedure called MRI guided focused ultrasound that stops some types of tremors.
"It involves high resolution MRI scanning as well as ultrasound technology," Jeff Elias, M.D., neurosurgeon at the University of Virginia Medical Center told American Health.
Other procedures involve invasive brain surgery, but the new scalpel-free surgery is the first to use ultrasound in the brain to treat tremors.
"We really have to be precise to within a millimeter to stop the tremor," Dr. Elias said.
The procedure is done in an MRI scanner that allows doctors to aim pulses of harmless ultrasound waves through a patient's skull to a targeted region within the brain known to be effective for treating some types of tremors. Thousands of ultrasound waves converge, heating up the area being treated, so that tremor-causing cells die.
"One of the real advantages of this technology is that it allows us the opportunity to test the patient during the treatment," Dr. Elias explained.
Billy and his doctors watched his tremor get better, and better during treatment. The end result?
"Almost immediately after the procedure my hand was as it is right now," Williams said.
It's an immediate fix to help get patient's back to a steady, normal life. Magnetic resonance guided focused ultrasound is currently in clinical trials at the University of Virginia Medical Center to treat patients with essential tremor - or ET, a progressive neurologic movement disorder. In the future, researchers plan to investigate the use of MRI guided focused ultrasound to treat other tremor disorders like Parkinson's, epilepsy and stroke.
Meghan Bradley UVA Health System Marketing Communications
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100% of every dollar goes to service the charities programs and services here in Palm Beach County and around the globe Not one cent in 8 years has ever gone to salaries, of any kind, to anyone. We are, from top to bottom all volunteers in service to the community. |
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MISSION STATEMENT
The American Health Society is a distinguished 13 year old multi-award winning preventative public health & wellness 501(c)(3) charity whose mission is in preventative healthcare, mental wellness, health education, literacy and advocacy aimed at preventing lifestyle based illnesses, diseases and the frailties of aging.
We have a strong "Social Green Philosophy" of Humanitarian Service through our American Volunteer Corps which has a global outreach in 46 countries with members in 37 US States.
J. Robert Gordon - CEO and Founder American Health Association
561-361-9091 |
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