American Health News and
Wellness Report Newsletter   
Prevention is a Cure (c)  
JANUARY 2012- Vol 13 Issue 48

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In This Issue
STOMACH CELLS AND ESOPHAGEAL CANCER
STEM CELL THERAPY REVERSES DIABETES
NEW COLONOSCOPY DEVICE
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Calendar of events

 

Monday, January 23rd. 2012 7:30 pm

The Boca Poetry Society

Boca Raton Community Center

150 Crawford Blvd, Boca Raton

561 361 9091 Free

 

Tuesday, January 24th 6:00 pm

ELF GRADUATION

Cici's on Hillsboro Blvd. & Powerline

561 361 9091 By Invitation Only

 

Saturday, January 28th. 2012 9 am to 10:30 am

Senior Friendship Club: A discussion group

Heritage Park West Library

5859 Via Flora, Delray Beach

561 361 9091 $1 donation to the charity

 

 

 

 President American Health Association
 J. Robert Gordon

Stomach cells and esophageal cancer 

Stomach Cells and Esophageal Cancer

(American Health Newswire)-- Experiments involving mice help provide new insight into what may cause a lethal form of esophageal cancer.

Research linked inflammation and bile acid reflux to the spread of cancer-causing stomach cells into the esophagus. This discovery may help pioneer strategies for treatment.

Esophageal adenocarcinoma is a cancer of the esophagus that is associated with acid reflux disease and Barrett esophagus (BE). BE is characterized by changes in the cells that line the lower esophagus, near the junction with the stomach. In BE, the normal flat esophageal cells are replaced by taller cells resembling those that line the stomach or intestine.

Although many questions about the disease remain unanswered previous research has suggested that BE may be caused by acid reflux disease and chronic inflammation.

"The precise origin of both esophageal adenocarcinoma and BE has been difficult to discern, in part because of the absence of useful experimental model systems that are genetically based," author Dr. Timothy C. Wang, from Columbia University was quoted as saying. "A major unanswered question that has been debated for decades is whether BE cells originate from the lining of the esophagus itself or from the region of the stomach called the cardia that is adjacent to the esophagus.

Dr. Wang and colleagues used a transgenic mouse model of BE and adenocarcinoma that significantly resembles human disease to explore the pathogenesis of the disease. The mice were engineered to express a specific molecule (interleukin-1) associated with chronic esophageal inflammation. The researchers discovered that inflammation and bile acid caused premature cells from the cardia to travel to the esophagus and give rise to the taller "columnar" cells characteristic of BE. Then they identified the exact signaling pathway that appeared to regulate differentiation of the cardia cells into columnar cells, which were associated with the origination of cancer in mice and humans.

The findings suggest that the abnormal cells linked with BE and esophageal adenocarcinoma originate in the cardia of the stomach and not the esophagus. "The fact that BE always begins precisely at the junction where the esophagus meets the stomach has never been explained, and now it seems clear that special consideration should be given to inflammation of the gastric cardia as it may represent a precursor of BE and esophageal adenocarcinoma," Dr. Wang said.

SOURCE: Cancer Cell, January 17, 2012

 

Stem cell therapy reverses diabetes

Stem Cell Therapy Reverses Diabetes

(American Health Newswire)- Type 1 diabetes is caused by the body's own immune system attacking its pancreatic islet beta cells and requires daily injections of insulin to regulate the patient's blood glucose levels.

A new method found in the BioMed Central's open access journal BMC Medicine uses stem cells from cord blood to reeducate the T cells in a diabetic's blood to restart the pancreatic function and reduce the need for insulin. In Stem Cell Educator therapy, lymphocytes were separated from a patient's blood over immobilized donated cord blood stem cells. After two or three hours in the device the revamped lymphocytes are returned to the patient. Progress was checked at 4, 12, 24 and 40 weeks after therapy.

After 12 weeks results showed an increase in C-peptide levels. C-peptide is a protein fragment created from insulin that can be used to determine how well beta cells are working. Levels increased at 24 weeks and remained the same at the end of the study, meaning that the patient's daily dose of insulin could be reduced. Also results showed that the glycated hemoglobin (HbA1C) indicator of long term glucose control also dropped for people receiving the treatment.

Dr Yong Zhao, from University of Illinois at Chicago, was quoted as saying, "We also saw an improved autoimmune control in these patients. Stem Cell Educator therapy increased the percentage of regulatory T lymphocytes in the blood of people in the treatment group. Other markers of immune function, such as TGF-beta1 also improved. Our results suggest that it is this improvement in autoimmune control, mediated by the autoimmune regulator AIRE in the CBSC, which allows the pancreatic islet beta cells to recover."

Source: BMC Medicine, January 2012

New colonoscopy device 

New Colonoscopy Device

STANFORD, CA (American Health Newswire) -- In the next twelve months, 150, 000 people will be told they have colorectal cancer and 50,000 will die from it.  The worst part is most of these deaths could have been prevented if the cancer would have been detected sooner.  Now, a new camera is giving doctors a better view to detect cancer before it becomes a killer.

Time on the driving range is time well spent for john reed and his son Zach. They're learning the game together.

"Whenever we start off, he always hits in the woods, unless there's a lake, then I hit it in the lake, not the woods, " Zachery Reed, John Reed's son, told American Health.

He may not be a straight shooter on the golf course, but when it comes to his health, john doesn't fool around.

"It has to start somewhere in your family, and I didn't want that to be me," John Reed said.
John's talking about colon cancer, and that's why the 51 year old recently had his first colonoscopy.

John is one of the first patients to use a new FDA approved device that gives doctors another view to the traditional colonoscopy, It's called third eye retro scope. A camera is snaked through five feet of your colon to detect polyps that could be an early sign of cancer.

"It's almost like a mushroom that grows inside the colon," George Triadafilopoulos, M.D., a gastroenterologist at Stanford University School of Medicine, explained. "The issue of the colonoscopy, is that's it's not perfect all the time. Sometimes these small polyps grow behind the fold, and they're not visualized at the time of the examination." 

The third eye fits through the traditional colonoscopy catheter.  Instead of just a forward facing camera, another tip comes through the catheter revealing a backward facing camera with an LED light.

"It's almost like having a rearview mirror in your car. As you drive forward, you can look through the mirror and see what's behind you, so you don't miss any spots," Dr. Triadafilopoulos said.

If a polyp is found, it can be removed immediately during the procedure.  A new study shows the device detects 41% more precancerous polyps for people who are at high risk and 23% more in people not at risk.

As for John, he was polyp free and can now concentrate on his game.

"Having a bad day doesn't stress me out. It's better than having to do other things, like have a colonoscopy," John said.

It's recommended that everyone start getting a colonoscopy at the age of 50.  How often after that depends on your family history and cancer risk.

 


100% of every dollar goes to service the charities programs and services here in Palm Beach County and around the globe Not one cent in 8 years has ever gone to salaries, of any kind, to anyone. We are, from top to bottom all volunteers in service to the community.
MISSION STATEMENT
The American Health Society is a distinguished 13 year old multi-award winning preventative public health & wellness 501(c)(3) charity whose mission is in preventative healthcare, mental wellness, health education, literacy and advocacy aimed at preventing lifestyle based illnesses, diseases and the frailties of aging. 
 
We have a strong "Social Green Philosophy" of Humanitarian  Service through our American Volunteer Corps which has a global outreach in 46 countries with members in 37 US States.

J. Robert Gordon - CEO and Founder
American Health Association
561-361-9091
Newsletter Editor and Communications Manager:
Suzanne Parent - suzanne@americanhealthfoundation.com