What You Should Know About NSAIDs 

NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) have been a wonder for many older dogs suffering from the aches and pains of arthritis.  Many of our senior canine companions have been given a few more years of enjoying their favorite play activities because of these drugs. The drugs in this group are now some of the most common prescription medications that older dogs take routinely.  

What are some examples of NSAIDs? Some NSAIDs commonly used in dogs include Rimadyl, Deramaxx, Metacam, Previcox, Zubrin, Novox and Etogesic.

How do the drugs work?

These drugs block the chemicals that cause inflammation and pain that comes with arthritis.  

Are there any side effects to NSAIDS?

Along with the good effects of the drug there is some risk for unwanted side effects. All drugs in this family have the potential to cause gastrointestinal ulcers and bleeding, and some even carry a slight risk of very damaging reactions in the liver. Dogs with underlying kidney, liver or gastrointestinal disorders are at higher risk for these consequences. The longer the drugs are used and the higher the dose the more risk there is for problems to arise. Any dog that needs to take any of these drugs for more than just a few days would need base-line blood work to assess their risk for problems and determine an appropriate blood work monitoring schedule. All dogs that take these drugs regularly need to have some periodic blood work monitored to look for liver and kidney problems and signs of bleeding ulcers.

How will I know if my dog is experiencing side effects?

If there is any loss of appetite, vomiting, diarrhea or tarry stool, NSAIDs should be stopped immediately and the veterinarian should be called. These signs can indicate an ulcer in the gastrointestinal tract. Ulcers can bleed and perforate and even be fatal if untreated.

How can I reduce the chance of side effects? 

Be sure to never give any two NSAIDs at the same time, and seek advice from you veterinarian when changing medications. You will be told to give your dog a few days off from one drug before going to the next. Never give steroids with NSAIDs. Always tell your veterinarian all drugs, vitamins and supplements you give to your dog.

Are NSAIDS available for cats?

Due to their unique liver metabolism, cats are unable to take these drugs safely, and are still waiting for their wonder arthritis drug. The dogs are the winners on this medical breakthrough!

For more information about canine arthritis, please see the pet care handout section of our website.