Dr. Mike's Health Newsletter
 Better Health Through Nutrition
  April 2010
In This Issue
Not-so-well-known vitamins and minerals

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Dr. Michael W. Roth

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Hi everyone!


This month actually starts part 1 of a series of related newsletters. All total, I'll be writing about 5 vitamins and 5 minerals that may or may not be well-known, but need to be expounded upon nonetheless. This month's newsletter is devoted entirely to Vitamin D3
The information that vitamins and minerals are necessary for vital health is fairly universal. But when it comes to supplementation, specific vitamin and mineral knowledge is limited to a common few such as: vitamins A, B, C, D and E, as well as calcium, magnesium, iron, and zinc. Yet, there are quite a few essential vitamins and minerals that, while lesser-known, are of equal importance. Our discussion will focus on several of these and will highlight their use and significance.

We begin with a vitamin that has been generating a lot of attention recently: vitamin D3. Most of us are generally familiar with vitamin D, but many do not realize that it is actually made up of two distinct forms: vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). Vitamin D2 is naturally present in very few foods and must be added to "fortified" products such as milk, juices and cereals. The lack of this form of vitamin D is attributed to bone disorders such as rickets. Vitamin D3 (cholecalciferol), is the form that is synthesized by the skin when it's exposed to the sun or ultraviolet light. 

Recent evidence suggests that D3 may be more effective than D2 in promoting calcium absorption and thus bone growth and remodeling. It prevents softening of the bones in both children (rickets) and adults (osteomalacia). It also helps modulate neuromuscular and immune function while reducing inflammation.

Individuals with limited sun exposure need to include good sources of vitamin D3 in their diet from food or supplements. Primary sources of this vitamin are fish and fish oils, beef liver, cheese and egg yolks. There are also an appreciable number of flowering plants in the Solanaceae family, that contain vitamin D3 and its hydroxylated derivatives.

Recommended D3 daily intake for infants to 50 years of age is approximately 200 IU (international units), between 51-70 years - 400 IU, and over 71 years - 600 IU.
There's a continuous debate about how much vitamin D3 is actually required by the body for health. Some recent schools of thought are elevating the amount of vitamin D3 recommendations to what I consider unhealthy or even dangerous levels. I've included a recent response I wrote to a doctor who felt my recommendations were outdated and that 2,000 to 5,000 mg of vitamin D3 should be consumed by all adults. 

Thank you for writing. Occasionally we receive questions about the quantity of vitamins, minerals, etc., in our products and the first thing I'd like to mention is that Dr. Drucker took great care to formulate the ratio and amounts of every single nutrient involved. Please keep in mind that when one is receiving nearly 100% of the included nutrients, megadoses are not necessary. Most supplements only achieve a cellular infusion percentage of 10-15%, so in order to receive what the body may require, it's often necessary to consume higher doses.

As far as the range mentioned, I think there is an increasingly dangerous practice of over-supplementation depending on the popularity of what I call the "vitamin du jour".  What I've noticed is that along with the growing focus on a particular vitamin comes recommendations to increase the amount of that vitamin. We only need look at the excessive consumption of vitamin C years ago that was supposedly the cure for many ailments. People began consuming several grams of supplemental vitamin C and the result was an increase in GI distress in various forms and severity. Those recommendations were subsequently lowered.

I personally think that some current vitamin D recommendations are set too high. There's always the potentially serious danger of hypervitaminosis from overconsumption of supplemental vitamin D (not from diet or sun exposure) which can lead to hypercalcemia and symptoms such as nausea, vomiting, poor appetite, constipation, weakness, confusion, heart arrhythmia, and kidney stones. There's also the consideration of those with health problems, such as liver or kidney disease or those taking thiazide-type diuretics which can make vitamin D overconsumption even more risky.

The Institute of Medicine (2009) recommends the same amount of daily vitamin D I've suggested. Although the amounts do vary depending on the source, they are generally close. For example, the AmericanAcademy of Pediatrics recommends closer to 300-400 IUs for children. Unofficially, we are seeing more recommendations for higher and higher levels of daily D. A level of up to 800 IUs for adults has been suggested for lowering the risk of osteoporosis, but that is nowhere near the megadose of 2000 to 5000 IUs you recommend.

Increasing the serum blood levels of vitamin D is not necessarily a good test to determine vitamin D absorption and utilization. Also, a complicating factor in determining how much vitamin D we need to get from diet or supplements is one's exposure to sunlight which can produce (naturally) and can convert several thousand IU's of beneficial vitamin D in as little as 15 minutes of exposure.

Logically and practically, if we look at a healthy diet, say the Mediterranean diet which consists primarily of grains, fruits and vegetables as well as some meats and fish, that person is getting at least 500-700 IUs of vitamin D from a 3 ounce piece of fish or meat. However, since most people are NOT following that kind of healthy diet, but are eating according to the Standard American Diet (SAD), they are generally consuming much more meat and dairy and are thus receiving far more vitamin D than the current DV recommendations.

In my opinion we should not make blanket megadose recommendations for vitamin D levels without taking into consideration individual differences which overconsumption may wind up doing more harm than good.

Thank you once again for your attention to this important vitamin!

Until next month I remain yours in good health.

Sincerely,

Dr. Mike