PQRI is a voluntary quality reporting program for eligible professionals who care for Medicare patients (Original Medicare only; not Medicare Advantage). For those quality measures you select, your records must document that you meet the quality standard. Here's a sample measure for ophthalmologists:

Cataracts: Comprehensive Preoperative Assessment for Cataract Surgery with Intraocular Lens (IOL) Placement Percentage of patients aged 18 years and older with a procedure of cataract surgery with IOL placement who received a comprehensive preoperative assessment of 1) dilated fundus examination; 2) axial length, corneal keratometry measurement, and method of IOL power calculation; and 3) functional or medical indication(s) for surgery prior to the cataract surgery with IOL placement within 12 months prior to cataract surgery. 

There is no enrollment or application process for PQRI. You simply begin reporting a PQRI companion code for each encounter you bill. The companion codes are different for each quality measure. There are additional qualifying requirements for participating with PQRI but most IPC Billing clients have several measures that apply to their specialty. IPC Billing will bill the companion PQRI code along with the other CPT codes for that visit. Payment of the 2% will be made the year following the reporting period year and must be reported to IPC Billing for posting.