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International Newsletter and Forum on Rigid Gas Permeable Contact Lenses, Corneal Shape, Health and Vision |
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Literature vs Clinical Practice
 It is hard for the academic literature to stay up to speed with the developments in our field. It oftentimes takes several months or even longer to see an article in print in our profession from the moment it was first submitted. If you include the time required to analyze the results and to write the article, especially if different co-authors are involved - it may take literally a year or more before something is published (sometimes years). In clinical practice, we want to rely on the latest developments - such as in myopia progression, for instance. But at the same time we need decent and reliable information so we don't get ahead of ourselves. Take corneal cross linking as another example. The newest technique that tries to stabilize keratoconus involves the 'epi-on' method, in which the epithelium does not have to be removed. While this method has gotten a lot of attention and momentum, only a handful of prospective, controlled studies on trans-epithelial cross linking are available at the moment. So how do we advise our patients? The same is true for myopia control - probably the most exciting development in our field maybe ever. But it may take another 5 years or so before we will see some evidence in the literature. What can we tell our patients in the meantime?
Eef van der Worp
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At a Cross Road?
 A s mentioned earlier, corneal cross linking (CXL) for treating corneal ectasia gets substantial attention in the media (see the article by James Owen and William Tullo in the August 2011 edition of Contact Lens Spectrum). The United States Food and Drug Administration recently granted 'orphan' drug designation for corneal cross-linking treatment for keratoconus to allow for more studies in this direction. Removing the epithelium with CXL, as is common practice now, seems to be a major disadvantage with the risk of corneal infections. Two surgeons (see the link below) report a corneal ulcer that developed after CXL with removal of the epithelium. On the other hand, practitioners have raised concerns about potential corneal irregularities post CXL - possibly more with the 'epi-on' method. Are we at a crossroads with CXL? See further the link below for a nice discussion on the topic from the American Academy of Ophthalmology.International Society of Refractive Surgery Outlook - August 2011
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Myopia Control & Orthokeratology
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Flat-out
 Flat-out one of the best lectures that I've ever attended is the one by Earl Smith III on myopia development and the potential optical treatment methods for controlling myopia. The Brien Holden Institute said about this: 'Professor Earl Smith III has been reshaping the way we think about our eyes for most of his career. In particular, our understanding of myopia has been revolutionised by his insights.' Under the title 'A Case for Peripheral Optical Treatment Strategies for Myopia,' Optometry & Vision Science published a paper based on Professor Smith's American Academy of Optometry Prentice Award Lecture in 2010.The paper is currently available in full format via the link below. In a table summarizing the relative efficacy of optical treatment strategies for slowing myopia progression, orthokeratology is among the current methods showing best results. The primary changes in corneal topography with orthokeratology are typically within the central 20°of the visual field; this typically leads to a change from relative peripheral hyperopia found at baseline to relative peripheral myopia after orthokeratology treatment, which is the refractive state that normally reduces axial growth in laboratory animals, according to Smith. The article also refers to a study from Japan by Kakita et al, in which larger reductions in progression rate were observed in individuals with higher degrees of central myopia. Optometry & Vision Science, September 2011
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The Digital Sclera
 In (R)GP lens fitting, respecting the cornea is of the utmost importance. Not only can it improve comfort of lens wear, it better protects corneal integrity (e.g. less chance of unwanted corneal irregularities) and even improves corneal physiology. Hence, digital fitting is on the rise. The same may now be true for scleral lenses. Optical Coherence Tomography (OCT) makes it possible to measure the shape of the anterior sclera. A poster by Hong-Gam et al at the most recent ARVO (association for research in vision and ophthalmology) meeting focused on this and demonstrated the success of using digital scleral lens fitting in 6 eyes of 5 patients. Greg Gemoules was one of the first to describe digital scleral lens fitting in the journal Eye & Contact Lens and now uses it routinely in his practice. Now we are waiting for better imaging techniques that will allow us to do full 'scleral topography' in all meridians. To be continued.
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Hydrops
One complication of keratoconus and other ectatic disorders is acute hydrops. Descemet's membrane ruptures, and the stroma and epithelium become edematous from the resulting inflow of aqueous. The symptoms can include blurry vision, pain, photophobia, excessive tearing and complaints of a "white spot" on the eye. Hydrops is known to resolve on its own, but the epithelial edema may worsen by wearing a scleral lens. Once the edema resolves, a patient may resume scleral lens wear. Sometimes the refraction may change as a result of the corneal flattening and may have resultant effects on higher-order aberrations. The dense scar may mislead clinicians to refer affected patients for a transplant, but exploring all refractive options with a scleral lens may render surgery unnecessary. Lynette Johns reports in this month's case report.
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Upcoming Events
- AAO, 12-15 Oct, Boston USA
- VDC 'Contact', 14-16 Oct, Munich DE
- GPLI Clinical Symposium, 23 Oct, Chicago USA
- BCLA Pioneers lecture, 23 Nov, London UK
- 28th cornea meeting, 3-4 Dec, Houston USA
- Global Specialty Lens Symposium, Jan 26-29 2012, Las Vegas USA
- San Diego Specialty Lens Symposium, Febr 24-26, San Diego USA
- NCC 2012, Maart 10-12, Veldhoven NL
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I-site is an educational newsletter that is distributed on a monthly basis and provides an update on rigid gas permeable related topics (scientific research, case reports and other publications worldwide). I-site is objective and non-political. Its editor Eef van der Worp, optometrist, PhD, FAAO, FBCLA, FIACLE, FSLS is a lecturer for a variety of industry partners, but is not related to any specific company. Please contact us at: i-site@netherlens.com.
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