IonSense, Inc
  February 2011
What's New with DART? 
The latest developments and news on DART Mass Spectrometry


We have some initial results here on the use of DART for looking at variations across a large number of samples, specifically for applications in food quality and forensics.  We also would like to hear about your recent work in DART, so please let us know.

Please have a look and contact me if you have any questions or comments. Thanks.


Brian Musselman
President and CEO
IonSense, Inc.
Good, Bad or Indifferent - That is the question

With the recent news of things not being what they should, we have been developing the DART approach for non-targeted screening and classification of products.  Based on the initial work of Jana Haslova's group at
the Institute for Chemical Technology in Prague, Czeck Republic, we analyzed a series of food oils to determine how DART can be used to classify quality and type.

We have also improved our ability to analyze a large number of samples by automating the deposition of samples onto the Microwell plate.  This is followed by automated analysis of the plate in the DART 3+D Scanner.  If you'd like information on our approach, please send me a note and we can give you the details.

Here we looked at 150 samples of oils and collected full scan DART mass spectra on our LCQ Deca. 
The low resolution peak tables were then transferred to a commercially available statistics program for analysis by principal component analysis (PCA) and the preliminary results are shown here.  Clearly the types are reasonable well separated.

Oils Classification  
This figure shows the classification of four types of food oils based on their DART mass spectra - Hazelnut Oil (HO), 100% Pure Olive Oil (POO), Mild Olive Oil (MOO), and Vegetable Oil (VO).  48 samples of each were diluted 1:10 in toluene and extracted using a MeOH:H2O.

We are taking steps to commercialize this approach by making the data handling and sample preparation simpler and faster.  We are applying this DART MS PCA method to food adulteration problems, product quality control, and forensics applications where customers may literally be looking for a needle in every haystack. We look forward to hearing your feedback on this approach, and perhaps taking a look at your data set.

Your DART Publications

As we mentioned recently, we have updated the applications area for DART and have begun to showcase all the wonderful things your folks are doing with DART.

If you have a recent publication that you would like to have added to the publications, just send us the citation and we will load up the abstract and biblio info.  Eventually we will have this so you can do it yourself, but in the meantime, just send it to us.  Thanks and let us know if you have any suggestions on improving your access to the latest research with DART.


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About IonSense

IonSense, Inc. provides open-air mass spectrometry solutions to the fields of food safety, forensics, drug development, and chemical analysis. They manufacture and develop direct analysis in real time (DARTŪ) technology licensed from JEOL USA, Inc. and atmospheric solids analysis probe (ASAP™) licensed from M&M Consulting.

DART and ASAP Sources are available for most commercial LC/MS systems.  Look here to see if your system is DART-ready.  And check here to see if your system is ASAP-ready.