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New research being hailed as a "real scientific breakthrough" shows that resveratrol could help improve the health of obese men.
Results of a study show that obese men who took resveratrol improved their metabolism as much as if they were on a strict low-calorie diet. In effect, taking resVida® resveratrol, the primary resveratrol in WineTime Bars, showed that without changing their diet or exercise habits the men's metabolic function improved, evidence of inflammation declined, fat deposits in their livers decreased and circulating triglyceride levels fell.
"While their bodies burned up the same amount of energy over a 24-hour period, their bodies' resting and sleeping metabolic rate declined and their muscles' use of fuel became more efficient-signs that they were using and storing calories more like athletes in training, than obese couch potatoes," wrote the Los Angeles Times.
The study, published in Cell Metabolism, was carried out by researchers at Maastricht University, in the Netherlands, in collaboration with TI Food and Nutrition, Wageningen University, DSM, and Ecole Polytechnique Fédérale de Lausanne (EPFL).
Eleven obese men were randomly given either a placebo or 150mg resVida resveratrol over a 30 day trial. After a four week washout period, the trial was repeated (crossed over) with all participants receiving the opposite supplement. The only incongruity: the men did not lose weight. Nevertheless, the results of the trial have been roundly acclaimed.
"...perhaps equivalent
to the...discovery
of antibiotics..."
"This is a real scientific breakthrough," said Professor Patrick Schrauwen who led the study.
Dr David L. Katz, director of the Prevention Research Center at Yale University School of Medicine said that the study, showing that resveratrol mimics the effects of calorie restriction in men (previously shown in studies with mice) was "stunning."
He went on: "We have the first clear evidence that a natural compound can exert the same profound effects on metabolism, weight and genes in humans. There is at least reason to hope a meaningful anti-aging effect could be appreciated as well. I rarely get excited by any one research paper. I am excited about this one."
Stephen Helfand of Brown University said: "The finding of molecules with such dramatic positive effects on age-related disorders and life span is a major conceptual leap forward for the field of aging research, perhaps equivalent to the effect of the discovery of antibiotics in treating infectious diseases."
Rafael de Cabo of the National Institute on Aging, who has been studying resveratrol in monkeys, said, "I think it's very promising. It's very significant."
In the Washington Post writer Rob Stein put it this way: "Many scientists have been excited about resveratrol since studies in yeast, fruit flies and laboratory mice indicated the substance could mimic the benefits of consuming a very low-calorie diet, which has been shown to extend longevity in many species. In the new study.resveratrol appeared to produce all the same effects in the human subjects as it had in animals, such as lowering the metabolic rate, cutting the accumulation of fat in the liver, reducing blood sugar, blood pressure, triglycerides and inflammation and boosting the efficiency of muscles."
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WineTime Bars were the featured Discovery of the Day on the 
