2010 In Vitro Alternatives Forum

Hotel Monaco, Old Town Alexandria, VA

October 18-19, 2010

 

- Program -

 

 

Day One - Monday October 18

12:00   Registration and Poster Viewing Available


1:00     Welcome and Opening of Forum

             - E. Hill, Institute for In Vitro Sciences (IIVS)


Session I:  Regulatory Challenges and Scientific Responses

1:05     Introduction to Session I - R. Curren, IIVS


1:10     TSCA Reauthorization Overview - J. Jones, EPA


1:35     Comments on TSCA Reform:

            Member of Congress - invited

            S. Amundson, Humane Society Legislative Fund (HSLF)

            R. Becker, American Chemistry Council (ACC)

  D. Fratz, Consumer Specialty Products Assoc. (CSPA)


2:15     Lessons Learned from Alternative Methods and their Validation for New

            Toxicology in the 21st Century -   T. Hartung, Johns Hopkins Univ/CAAT


2:40     Lessons Learned in the ToxCast High Throughput Screening Program

  -  R. Kavlock, EPA


3:05     QSAR Modeling of Toxicological Responses: Leveraging the Past to

Jump Start the Future - C. Yang, Altamira LLC


3:30     Coffee Break and Poster Viewing


4:00     Update on EPA Activities on Animal Alternatives - T. Levine, EPA


4:25     A Cooperative Effort Towards a Non-animal Testing Strategy for Specific EPA    

            Regulated Products - R. Curren, IIVS


4:45     FDA Informatics and Computational Safety Analysis Program - D. Benz, FDA


5:10     Closing Remarks and Questions


5:15     A New Scientific Society: American Society for Cellular and

            Computational Toxicology (ASCCT) - E. Hill, IIVS and K. Sullivan, PCRM


5:30     Cocktail Reception:

William & Eleanor Cave Award Presented by ARDF

 

 

 

Day Two - Tuesday October 19

8:00     Continental Breakfast and ASCCT Informational Meeting- Open to all Attendees

 

Session II:  In Vitro Approaches to Identify Skin Sensitizers

9:00     Introduction to Session II - R. Landsiedel, BASF


9:05     Translation of Allergenic Contact Dermatitis Processes in Humans to

             In Vitro Test Systems - A. Gaspari, Univ. of Maryland, Dept. of Dermatology


9:30     Application of Peptide Reactivity Assays for Screening Skin Sensitization

  Potential - F. Gerberick, The Procter & Gamble Company


9:55     ECVAM Prevalidation Study on Skin Sensitization Alternatives: Update on

            Progress - D. Basketter, DABMEB Consulting 


10:20  The COLIPA Research & Method Development Program for Identifying & 
           Characterizing Chemical Skin Sensitizers without Animal Testing 

             - P. Aeby, COLIPA


10:45   Current Status of human Cell Line Activation Test

             - H. Sakaguchi, Kao Corporation

  

11:10   ICCVAM Progress in Advancing Alternative Safety Testing Methods for

            Assessing AllergicContact Dermatitis - W. Stokes, NIEHS/ICCVAM


11:30   Poster Viewing

12:00   Lunch

 

Session III: New In Vitro Approaches Utilizing 3D Tissue Models

1:00     Introduction to Session III: A. De Smedt, Johnson & Johnson


1:05     3D Tissue Models: Their Role in 21st Century Toxicology - R Curren, IIVS


1:20     Measuring Depth of Injury in Irritation Models

  - J. Jester, UCI Department of Ophthalmology


1:45     Integrating In Vitro Models into Risk Assessment

            - A. De Smedt, Johnson & Johnson


2:10     Use of 3D Models in Genotoxicity Assays - M. Aardema


2:35     Primary 3D-Aggregating Brain Cell Cultures for Neurotoxicity and  

            Developmental Neurotoxicity Testing - E. van Vliet, Johns Hopkins Univ/CAAT


3:00     In Vitro Approaches to Inhalation Toxicology

            - M. Gaça, British American Tobacco


3:25     Coffee Break and Poster Viewing

 

Session IV: Recent Advancements from In Vitro Manufacturers

3:55     Introduction to Session IV - Dan Bagley, Colgate-Palmolive


4:00     Developing Microfluidic Systems for Robust In Vitro Testing Using

            Human Cellsand Tissues - M. Yarmush, Hurel Corporation


4:20     Predicting Developmental Toxicity with Human Embryonic Stem Cells

And Metabolomics - E. Donley, Stemina Biomarker Discovery


4:40     Screen Early to Understand your Compound's Toxicity Profile

-  J. Srinivasan, Accelrys


5:00     Close of Forum