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Magnesium, een mineraal dat weinig in onze voeding
voorkomt, speelt een rol bij (spier)spanning, de
prikkeloverdracht, het hartritme, de botopbouw, werkt
ontspannend en is onmisbaar voor de aanmaak van
enzymen en hormonen. Het kan verzuring tegen gaan
en herstelt een verstoorde klierwerking. Magnesium is
��n van de belangrijkste mineralen in het lichaam dat
ook borg staat voor een uitstekende nachtrust. Omdat
magnesium bij zoveel processen in het lichaam
betrokken is en wij relatief weinig binnen krijgen (o.a.
door verschraling van de voedingsbodem), hebben wij
massaal een te kort aan dit mineraal.
Een degelijk magensium supplement, al of niet in
combinatie met calcium en kalium zorgt voor een
rustige en herstellende slaap. Volgens de
wereldgezondheidsorganisatie heeft een volwassene
dagelijke 460 milligram magnesium nodig. De
westerse voeding zou gemiddeld 120 milligram
magnesium per dag leveren. Met deze cijfers lijkt het
logisch waarom zoveel mensen klagen over
bijvoorbeeld slaapproblemen.
Sinds januari 2010 geldt voor de mineralen dat voor
de vorm waarin ze mogen worden verhandeld een
zogenaamde positieve lijst gehanteerd moet worden.
Op deze lijst komt helaas het (goed opneembare en
veilige) aspartaat niet voor. Gelukkig mogen we dit
jaar nog "uitverkopen". Dus dat doen we !
Op de volgende magnesiumaspartaatpreparaten
geven we (zover de voorraad strekt) een korting van
30%.
Magnesium aspartaat comp tabletten (FYTOCURA)
ingredienten per tablet : magnesium aspartaat (700mg, 50mg elem Mg) alfalfa (100mg), spirulina, chlorella, blue klamath en groene gerstesap (allen 50mg); samen een prachtige matrix om de magnesium beter op te nemen. Magnesium 5+ capsules (FYTOCURA)
ingredienten per capsule : 167mg Magnesium L-aspartaat (20%), 167mg Magnesium aminochelaat (20%), 167mg Magnesium glyconaat (15%), 167mg Magnesium orotaat (7,5%), 167mg Magnesium ascorbaat (10%), 70 mg Alfalfa (extractum siccum), 70 mg Spirulina, 70 mg Chlorella. actieprijzen :
per 100 stuks : 14,00 euro i.p.v. 20,00 per 250 stuks : 28,35 euro i.p.v. 40,50 per 500 stuks : 50,05 euro i.p.v. 71,50 Ook verkrijgbaar via Holland Pharma (Varuvo).
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In this issue we find articles on the potential use of
mushroom nutrition in degenerative neurological
conditions, enzyme analysis on Agaricus blazei,
Hericium erinaceus, Polyporus umbellatus and
Pleurotus ostreatus.
Finally, we review the final results of Dr. Silva Coutos
clinical work on the use of Coriolus versicolor
supplementation in HPV lesions and viral load.
Deze editie is door omstandigheden pas nu in
gedrukte versie tot ons gekomen. De MRL-abonnees
krijgen hem automatisch per post. Indien u
geinteresseerd bent, kunt u natuurlijk altijd vragen.
Maar gelukkig kunt u de hele editie in kleur
downloaden.
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Vanaf deze uitgave zullen wij iedere keer aan een
tinctuur meer aandacht besteden in een ongewone
setting. Deze keer Chrysanthellum americanum of
indicum.
Randomized placebo-controlled trial of a flavonoid-rich
plant extract-based cream in the treatment of rosacea
D Rigopoulos*, D Kalogeromitros, S Gregoriou,
JM Pacouret, C Koch, N Fisher, K Bachmann, M
Brown, E Schwarz, E Camel�, A Katsambas
Department of Dermatology, University of Athens, 'Andreas Sygros Hospital', Athens, Greece, IRIS, Institut de Recherches et d'Innovations Scientifiques, Paris, France, Private Practice, Germany, �IEC Company, France. Background Biological research suggests that
vascular changes may play a major role in rosacea
pathogenesis. Chrysanthellum indicum is a plant-
based extract containing a unique combination of
phenylpropenoic acids, flavonoids and saponosids,
and has a well-documented effect on vascular wall
permeability and increase of the mechanical
resistance of capillaries.
Objective To determine the efficacy and safety of a
cream containing 1%C. indicum extract with vitamin P
properties in the treatment of rosacea.
Results Treatment with the C. indicum extract-based
cream resulted in significant improvement (P < 0.05)
in severity of erythema, overall rosacea severity
compared to baseline and placebo, and investigator
and patient overall efficacy assessment scores (P =
0.046 and P = 0.001, respectively) compared with
placebo scores. Adverse reactions were mild, and did
not differ between the C. indicum extract-based cream
and the placebo groups.
Conclusion Chrysanthellum indicum extract-based
cream is an effective and well-tolerated topical agent
for the treatment of moderate rosacea. The mode of
action of the active ingredient suggests that additional
efficacy might be expected from combination with
other topical treatments.
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Triterpenes augment the inhibitory effects of
anticancer drugs on growth of human esophageal
carcinoma cells in vitro and suppress experimental
metastasis in vivo.
Yamai H, Sawada N, Yoshida T, Seike J, Takizawa H,
Kenzaki K, Miyoshi T, Kondo K, Bando Y, Ohnishi Y,
Tangoku A. (Department of Thoracic, Endocrine
Surgery and Oncology, Institute of Health Bioscience,
The University of Tokushima Graduate School,
Tokushima, Japan.)
The antineoplastic effects of combinations of
anticancer drugs (5-fluorouracil, irinotecan and
cisplatin) and triterpenes (ursolic acid, betulinic
acid, oleanolic acid and a Japanese apricot
extract (JAE) containing triterpenes) on esophageal
squamous carcinoma cells were examined by the
WST-8 (2-(2-methoxy- 4-nitrophenyl)-3-(4-nitrophenyl)-
5-(2,4-disulfophenyl)-2H-tetrazolium, monosodium
salt) assay in vitro and by an animal model in vivo.
Triterpenes and JAE showed additive ........................
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Betulinic acid augments the inhibitory effects of
vincristine on growth and lung metastasis of B16F10
melanoma cells in mice.
Sawada N, Kataoka K, Kondo K, Arimochi H, Fujino H,
Takahashi Y, Miyoshi T, Kuwahara T, Monden Y,
Ohnishi Y. (Department of Oncological and
Regenerative Surgery, School of Medicine, The
University of Tokushima, Tokushima 770-8503,
Japan.)
We examined the antitumour effect of a combination of
betulinic acid (BA) and vincristine (VCR) on murine
melanoma B16F10 cells in vitro and in vivo. Betulinic
acid, a pentacyclic triterpene, showed a synergistic
cytotoxic effect on melanoma cells by combinational
use of VCR. Betulinic acid and VCR induced cell cycle
arrest .................
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OP DE MAT viel the Journal of Chinese Medicine met
een aantal aardige artikelen Onder anderen
ANALYSIS OF THE EFFECTIVENESS OF TCM
TREATMENT OF MULTIPLE SCLEROSIS van Dan
Jiang.
Modern biomedicine currently does not have a
satisfactory method to treat multiple sclerosis (MS). In
this paper the author summarises her experience of
treating MS using acupuncture and Chinese herbal
medicine by analysing the treatment of 20 patients.
The advantages and disadvantages of different
treatment modalities are assessed, with emphasis
on the importance of choosing the correct method and
dosage of acupuncture in order to successfully
manage the various symptoms and stages of MS. In
the experience of the author the key to successful
treatment of MS is an integrated approach that
employs both TCM pattern differentiation and
biomedical diagnostic findings.
en ook (echt leuk :
CONGEE ‑ LONGEVITY FOOD FOR LIFE van
Rebecca Erlewein
Congee ‑ creamy rice soup ‑ is a
nourishing and
easily assimilated food and constitutes an ideal meal
for patients with digestive difficulties or qi and blood
deficiency. It is, however, very different from
contemporary Western foods, and because few
enticing cooking instructions are available it can be
difficult to get patients to follow advice to eat it. This
article gives an introduction to the use of congee in the
diet, a recap of the functions of the digestive system
and clear instructions for congee preparation. A
handout designed for patients with congee recipes
and a tick list for additions can be downloaded from
the author's website.
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Ook OP DE MAT viel Phytomedicine. Heel interessant
om eens te zien hoe de wetenschappers onze
praktische arbeid aan het onderbouwen zijn en
blijven. Bijvoorbeeld het eerste artikel :
Wormwood (Artemisia absinthium) suppresses
tumour necrosis factor alpha and accelerates healing
in patients with Crohn's disease - A controlled clinical
trial. van Simone Krebs, Talib N. Omer, Bilal Omer.
Suppression of tumour necrosis factor alpha (TNF-
α)
and other interleukins by wormwood (Artemisia
absinthium) extracts were reported recently in in vitro
studies. The aim of the present study was to find out if
this effect can be also be observed in Crohn's
Disease (CD) patients where TNF-α appears to
play
an important role. In a controlled trial, 10 randomly
selected patients suffering from CD were given in
addition to their basic CD therapy 3�750 mg dried
powdered wormwood for 6 weeks. Ten patients, also
randomly selected who met the inclusion criteria
served as control group. Minimum score of 200 on
Crohn's Disease Activity Index (CDAI) was required at
baseline for inclusion in each group. Patients who
received infliximab or similar were excluded from the
trial. TNF-α level in serum were measured at
baseline, and after three and six weeks. During this
period all concomitant CD medications was
maintained at the baseline dose levels. Average
serum TNF-α level fell from 24.5�3.5 pg/ml at
baseline to 8.0�2.5 pg/ml after six weeks. The
corresponding levels in the control group were
25.7�4.6 (week 0), and 21.1�3.2 (week 6). On the
clinical side, CDAI scores fell from 275�15 to below
175�12 in wormwood group with remission of
symptoms in eight patients (CDAI score below 170 or
reduction by 70 points), compared to only two in the
placebo group (CDAI of placebo group 282�11 at
baseline and 230�14 on week 6). IBDQ also reflected
accelerated clinical response with wormwood. Of
clinical significance were the findings that wormwood
also improved mood of the CD patients, as reflected
in Hamilton's Depression Scale. These findings
provide a base to test wormwood in clinical conditions
thought to be mediated by increased production of pro-
inflammatory cytokines such as TNF-α.
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De Vereniging Van Arts en Auto geeft een blad uit en
dat heet : Arts en Auto. Dat blad heeft een enquete
gepubliceerd onder haar lezers om de mening te
peilen over alternatieve geneeswijzen. Zoals te
verwachten waren de vragen nogal sturend en vielen
er soms open gaten.
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In vitro antioxidant activity of Juglans regia L. bark
extract and its protective effect on cyclophosphamide-
induced urotoxicity in mice.
Bhatia K, Rahman S, Ali M, Raisuddin S. (Department
of Medical Elementology and Toxicology, Jamia
Hamdard (Hamdard University), New Delhi, India.)
Walnut (Juglans regia L.) bark has been claimed to
possess anti-inflammatory, blood purifying,
anticancer, depurative, diuretic and laxative activities. It
contains several therapeutically active constituents,
especially polyphenols. We studied the antioxidant
potential of aqueous extract of walnut bark and its
modulatory effect on cyclophosphamide (CP)-induced
urotoxicity in Swiss albino male mice. Free radical-
scavenging activity of extract was assessed ........
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Effects of chronic administration of Melissa officinalis
L. extract on anxiety-like reactivity and on circadian and
exploratory activities in mice
Alvin Ibarraa, Nicolas Feuillereb, Marc Rollerb, Edith
Lesburgerec and Daniel Beracochea.
This study aimed to determine the effects of chronic
(15 consecutive days of treatment) per os
administration of Melissa officinalis L. extract
(Cyracos®, Naturex) on anxiety-like reactivity in mice.
As measured by HPLC, Cyracos® contains significant
amounts of rosmarinic acid and the triterpenoids
oleanolic acid and ursolic acid, which inhibit gamma-
aminobutyric acid transaminase (GABA-T) activity and
increase GABA levels in the brain (Awad et al., 2007;
Awad et al., 2009).
Thus, we evaluated ...............
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Study Finds Echinacea/Sage Throat Spray as Effective
as Chlorhexidine/Lidocaine for Acute Sore Throat
Schapowal A, Berger D, Klein P, Suter A.
Echinacea/sage or chlorhexidine/lidocaine for treating
acute sore throats: a randomized double-blind trial.
Europ J Med Res. September 1, 2009;14(9): 406-412.
Sore throat is one of the most common ailments in
general medical practice. Fewer than 20% of people
with a sore throat are infected with Streptococcus and
require antibiotic treatment, and sore throat is typically
treated with pain relievers alone. Common over-the-
counter drugs for relief of sore throat pain include
analgesics and throat sprays (containing numbing
agents or antibacterial ingredients). Echinacea
(Echinacea purpurea) and common sage (Salvia
officinalis) have anti-inflammatory, antimicrobial, and
immune modulating properties and are also used to
relieve sore throat and other symptoms of upper
respiratory tract infections. The purpose of this study
was to compare the effectiveness of a throat spray
containing echinacea plus sage with a throat spray
containing chlorhexidine plus lidocaine in relieving
sore throat pain.
The authors conclude that the throat spray containing
echinacea plus sage was as effective in reducing sore
throat symptoms and as well tolerated as the spray
containing chlorhexidine plus lidocaine. They suggest
that the spray is an effective alternative to oral and
spray products containing analgesic and anesthetic
drugs. The authors address the possibility that
providing ibuprofen to the subjects may have biased
the results. However, a subanalysis showed that the
results were the same, regardless of whether or not
subjects took ibuprofen.
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