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| Free Thoughts | Breathe. Let go. And remind yourself that this very moment is the only one you know you have for sure
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Please reply with feedback or questions to newsletter@salisburypediatrics.com. I will try to answer as many questions via the newsletter as possible. As always be well and love your children!
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| Dr. Magryta |  | |
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| Issue: #6 | January 30, 2012 |
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Volume 2, Letter 6
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January 30, 2012
Acetaminophen and lung disease - Is there a link?
Acetaminophen/Tylenol/paracetamol - we use this drug to help with pain, fever or malaise. It was developed in the early 1900's and was brought to market in 1953. It is believed to inhibit the enzyme cyclooxygenase 2 which in turn reduces the production of pro inflammatory chemicals like arachadonic acid,
thereby, providing it's user with relief. It is removed from the body by the liver and also utilizes glutathione for clearance. Our cells need glutathione to detoxify unwanted chemicals in our system. Here is where the rub comes in.
It happens to be the subject of much controversy regarding the asthma epidemic. In a recent Pediatrics article from December 2011, the author, John McBride, a pulmonologist, reviews the data. He sees a plausible mechanism for the hypothesis that asthma is on the rise because of the overuse of Tylenol in young children when they are sick with respiratory viral infections. The acetaminophen is depleting the glutathione in the lungs and reducing the bodies natural toxin clearing mechanism. This makes the child's lung tissue susceptible to the chemical.
I believe that chemicals can alter the cell's DNA at the lung tissue thereby epigenetically inducing asthma. We have seen this model occur with other diseases like diabetes (see Duk Hee Lee's work, Volume 1, letter 2) There is evidence that chemicals believed to cause trouble include air pollution particulate matter, cigarette smoke and other in house aerosolized particles that are synthetic. See www.EWG.org. Proving direct causation is always difficult.
I am not saying that this is the only cause of the asthma epidemic. To the contrary, it is only a likely player in the game along with poor maternal health while pregnant, other drug exposures and poor childhood nutrition.
In his article, he states the obvious. If there is a chance that this drug could be triggering asthma in children, then why are we not discussing it with our patients and counseling them about judicious use.
I still hear it said over and over again to rotate Tylenol and ibuprofen for fever. There is no basis for this recommendation. Now we have another reason to avoid this archaic treatment regimen.
Here is another interesting study:
Leffers, H, et al (2010). "Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat". Human Reproduction 25 (1): 235-244.
My take home point today: Use this drug only when you have to.
Just thinking out loud,
Dr. Magryta
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| Protein |
Episode 5 - Protein What macronutrient is more important post workout for building muscle? Protein or carbohydrate?
It turns out that both are important, but protein is by far more important for building muscle.
Carbohydrates can help reduce protein breakdown post workout. If you take a placebo drink versus a carbohydrate drink and measure muscle breakdown post workout, you will find that you are more likely to maintain muscle mass with a carbohydrate drink. Ideally, you gain many benefits with a good post workout carbohydrate meal/drink. However,....
If you workout, you will build muscle. If you eat or drink protein, you will build muscle. But --- If you do both, then protein synthesis is compounded. This is the key if you want to build muscle and gain strength.
Proteins are made up of amino acids that are the building blocks of muscle. There are 9 essential amino acids*. We have to ingest these amino acids by way of complete proteins to build our muscles. Some examples of complete proteins are all meats and fish as well as soybeans and quinoa. Other foods have partial volumes of the essential amino acids - for example, grains like amaranth are excellent as well as other legumes like chick peas.
Giving protein after a workout dramatically reduces muscle breakdown and fatigue by maintaining a positive nitrogen balance. This is well beyond that of a carbohydrate meal. This is a good thing for us old folks but equally important for the young highly trained athlete.
Next Week Timing of amino acids and protein
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| Physical Therapy Corner with Joel | |
Function
We know that genetics play a vital role in development and performance. It has been said that 30% of performance is influenced by genetics, 20% injury & disease, and 50% lifestyle. Gary Gray added another component.....FUNCTION!!!
Where does it come from?? If we trigger a response or a reflex over and over in our muscles, then we will have created a motor pattern (skill) that is engrained into our nervous system. We know that muscles function in a coordinating fashion, so in order to enhance performance, it requires that you refine the movement pattern and not just isolate specific muscles. Doing isolated curls is not in the best interest of function unless all you want is a big bicep.
Obviously, one may say "ok, now i feel mastery in the movement (eg. broad jump). Why am i not the best player on the team?" Learning the movement pattern is just the beginning, now you add speed and strength to the equation. Performance is open ended.
Gray's teachings stemmed from early childhood through adulthood where a stimulus illicits a response that becomes a skilled reaction and later a skilled performance. We live in a 3-D world and we enjoy all planes of motion meaning that we have the ability to move forward, backward, laterally, rotationally, up & down (squat/step), climb, jump, push/pull, lift, throw, catch, hit, etc... and when done repeatedly with good technique/quality of movement, that is what our nervous system recognizes and duplicates.
Sedentary lifestyle does nothing to facilitate the ingenious qualities available to the human body. As a parent of a child, encourage playing in the yard/park/court/etc.... As a teenager, enjoy all sports. Band is a sport, cheerleading is a sport, badminton is a sport, biking is a sport, football,basketball,baseball, tennis, etc.. As an adult, stay intelligently competitive. Later in life, you will find that it is you against you and that the choice of activity, or lack of, will be the deciding factor in maintaining health and FUNCTION!!
Joel Burgess
Xtra Performance and Physical Therapy
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The newsletter archive in the links section is officially working. New readers can now go back in time to learn about the future!
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Recipe of the Week
| Shrimp and Chimichurri from wholeliving.com
Ingredients:
1-2 pounds of large peeled wild caught shrimp
1/2 tsp kosher salt
1/4 tsp fresh ground pepper
Chimichurri:
1/3 cup fresh chopped basil
1/4 cup fresh minced chives
1/4 cup fresh chopped parsley
2 Tbsp fresh chopped mint
1 1/2 tsp fresh minced garlic
1 1/2 tsp fresh squeezed lemon juice
1 cup extra virgin olive oil
Chili flakes if desired
Directions:
Combine all Chimichurri ingredients together.
Soak wooden skewers in water X30 minutes.
Heat grill to high.
Season with salt and pepper and then drizzle with oil and toss to coat.
Grill for 2 minutes per side.
Remove and coat with Chimichurri.
Serve with other grilled veges and a side of whole grain rice.
Enjoy,
Dr. M
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| Extras | |
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From Livestrong.com
FOODS HIGH IN ESSENTIAL AMINO ACIDS
Sep 28, 2010 | By Barbara Diggs
Amino acids are the chemical units that constitute protein. While the human body can manufacture most amino acids on its own, it cannot synthesize certain amino acids in sufficient amounts to meet the body's needs. Such amino acids are called "essential amino acids" because it is crucial that the body acquires them through dietary sources. A deficiency in essential amino acids can result in numerous health problems from indigestion to stunted growth to infertility.
EGGS
Eggs are considered a complete protein, which means they contain all the protein the body needs, including each of the nine essential amino acids. According to the National Egg Coordinator Committee, one large egg contains 6.3 g of protein, which amounts to about 10 percent of the daily recommended allowance of protein for an adult. The NECC also reports that the quality of egg protein is so high that scientists use the egg as a baseline to measure the quality of protein in other foods.
MEAT
Animal meats such as beef, pork, chicken and turkey are complete proteins. According to the Centers for Disease Control and Prevention, a 3-oz piece of meat contains approximately 21 g of high-quality protein. However, even though you'll get all the essential amino acids you need from meat, the CDC recommends that you select the leanest cuts of red meat or stick with poultry to avoid consuming too much saturated fat along with the protein.
SOYBEANS
Soybeans are the only plants considered a complete protein. Tofu, edamame, soy nut, miso or even soy milk are all good sources of the nine essential amino acids--and have the added benefit of being low-fat. Recent research has indicated that sometimes soy in the diet may be harmful, however. MayoClinic.com notes that soy may affect the thyroid hormone levels in infants and may stimulate tumor growth in patients with hormone-sensitive cancers due to its estrogen-like properties.
QUINOA
Quinoa is a seed rich essential amino acids. According to World's Healthiest Foods, it is the perfect source of protein for vegans as, not only is it a complete protein, it is packed with the essential amino acid Lysine, which is fundamental to tissue development and repair. One cup of cooked quinoa contains 9 g of protein.
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Copyright � 2010-2012 Christopher J. Magryta, MD. Readers, please note: The information provided in this newsletter is for educational and informational purposes only. It is not a substitute for advice and treatment provided by your physician or other healthcare professional and is not to be used to diagnose or treat a health issue.
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Chris Magryta
Salisbury Pediatric Associates
Touchstone Pediatrics |
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