Obesity and Breast Cancer What is the Link?
 Breast cancer is the leading cause of cancer death in non-smoking women. Modern methods of treatment have proven very helpful in reducing the number of deaths due to this common cancer.
Unfortunately, the current epidemic of obesity is only worsening the problem for many women. Let's take a look at the facts and the science behind this problem.
Do you recognize these women: Elizabeth Edwards, Linda McCartney, and Rachel Carson. These are women who lost their battle with breast cancer. Others like Sandra Day O'Conner, Cokie Roberts, and Gloria Steinem have not. No other cancer strikes more women. Only lung cancer claims more lives.
One thing is clear about post-menopausal breast cancer: Obesity increases the risk. While you can't eliminate your cancer risk, combining proper screening, early treatment, and aggressive weight management can reduce your risk of dying from this condition.
Fat cells produce an estrogen-like hormone. Excess estrogen has long been known to promote breast cancer. The main source of estrogenic effect in obese post menopausal women is their fat tissue.
High insulin levels may promote cancer growth. In one study, researchers found that women with the highest insulin levels were 2.5 times more likely to be diagnosed with breast cancer than those with the lowest levels (J. Natl. Cancer Inst. 101: 48, 2009). Insulin levels increase with weight gain. The highest levels are found in those with adult-onset diabetes and "pre-diabetes" or metabolic syndrome.
Obese individuals have higher levels of inflammation. Fat cells produce an array of different substances. Some of these are known to promote inflammation. In small amounts, they may be beneficial. But in larger amounts these substances may promote damage to vital body tissues and actually increase cancer risk.
As people continue to live longer lives and the rates of heart disease decline, cancer looms as an increasing cause of death for many Americans. Starting on a program of healthy eating and weight loss may help reduce your risk. |